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LOC127398813 OCT4-NANOG hESC enhancer GRCh37_chr3:137485043-137485739 [ Homo sapiens (human) ]

Gene ID: 127398813, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127398813
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr3:137485043-137485739
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127398813 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (137766201..137766897)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (140506806..140507502)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (137485043..137485739)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374126 Neighboring gene NANOG hESC enhancer GRCh37_chr3:137366045-137366546 Neighboring gene NANOG hESC enhancer GRCh37_chr3:137413714-137414679 Neighboring gene nucleophosmin 1 pseudogene 17 Neighboring gene SOX14 promoter region Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr3:137486565-137487111 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:137486017-137486564 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:137490617-137491277 Neighboring gene long intergenic non-protein coding RNA 1210 Neighboring gene SRY-box transcription factor 14 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:137526407-137526911 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:137526912-137527415 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:137533769-137534270 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:137585401-137586318 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:137587591-137588092 Neighboring gene heat shock protein family A (Hsp70) member 8 pseudogene 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_100779.1 

    Range
    101..797
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    137766201..137766897
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    140506806..140507502
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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