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LOC127400442 NANOG hESC enhancer GRCh37_chr4:24414779-24415480 [ Homo sapiens (human) ]

Gene ID: 127400442, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127400442
Gene description
NANOG hESC enhancer GRCh37_chr4:24414779-24415480
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127400442 in Genome Data Viewer
Location:
chromosome: 4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (24413156..24413857)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (24394852..24395555)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (24414779..24415480)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374527 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:23789763-23790962 Neighboring gene PPARG coactivator 1 alpha Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_77881 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:23887769-23888345 Neighboring gene VISTA enhancer hs2346 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:23933777-23934617 Neighboring gene NANOG hESC enhancer GRCh37_chr4:23974350-23974892 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:23981005-23981707 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:24000845-24002044 Neighboring gene NANOG hESC enhancer GRCh37_chr4:24031602-24032103 Neighboring gene Sharpr-MPRA regulatory region 2780 Neighboring gene Sharpr-MPRA regulatory region 10171 Neighboring gene uncharacterized LOC124900679 Neighboring gene NANOG hESC enhancer GRCh37_chr4:24268492-24268993 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:24323096-24323895 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:24332192-24332760 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:24350443-24351174 Neighboring gene uncharacterized LOC124900678 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:24472858-24473359 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15315 Neighboring gene uncharacterized LOC124900681

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_102405.1 

    Range
    101..802
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    24413156..24413857
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    24394852..24395555
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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