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LOC127400735 OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49148795-49149632 [ Homo sapiens (human) ]

Gene ID: 127400735, updated on 12-Sep-2024

Summary

Gene symbol
LOC127400735
Gene description
OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49148795-49149632
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

See LOC127400735 in Genome Data Viewer
Location:
chromosome: 4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (49146778..49147615)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (49105671..49106503)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (49148795..49149632)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA70 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21551 Neighboring gene cell wall biogenesis 43 C-terminal homolog Neighboring gene triosephosphate isomerase 1 pseudogene 4 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49092970-49093748 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49093749-49094527 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49094528-49095306 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49095307-49096084 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49096085-49096864 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49096865-49097642 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49097643-49098421 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49098422-49099199 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49099200-49099978 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49099979-49100757 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49100758-49101536 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49101537-49102314 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49102315-49103094 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49103095-49103872 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49103873-49104650 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49104651-49105428 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49105429-49106208 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49106209-49106986 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49106987-49107766 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49107767-49108544 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49108545-49109324 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49109325-49110102 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49110103-49110880 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49110881-49111658 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49111659-49112438 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49112439-49113216 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49113217-49113994 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49113995-49114772 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49114773-49115552 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49115553-49116330 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49116331-49117108 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49117109-49117886 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49118401-49119098 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49119099-49119795 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49119796-49120492 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49120493-49121189 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49121190-49121887 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49121888-49122584 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49122585-49123281 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49123282-49123977 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49123978-49124675 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49124676-49125372 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49126071-49126766 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49125373-49126070 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49126767-49127464 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49127465-49128160 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49128161-49128857 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49128858-49129553 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49131647-49132342 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49132343-49133040 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49133737-49134434 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49135131-49135828 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49134435-49135130 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49135829-49136524 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49136525-49137222 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49137223-49137918 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49139313-49140009 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49140010-49140705 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49140766-49141340 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49141341-49141914 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49142489-49143062 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49143063-49143636 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:49143637-49144210 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49144785-49145357 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49145444-49146282 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49146283-49147119 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49147120-49147957 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr4:49147958-49148794 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49149633-49150470 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49150471-49151308 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49151309-49152144 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr4:49152255-49152881 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr4:49152882-49153507 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49153693-49154210 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49154805-49155794 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49155795-49156783 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:49156784-49157772 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:49157773-49158761 Neighboring gene uncharacterized LOC101927209 Neighboring gene OCT4 hESC enhancer GRCh37_chr4:49168367-49168868 Neighboring gene sorting nexin 18 pseudogene Neighboring gene sorting nexin 18 pseudogene 23

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_102698.1 

    Range
    101..938
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    49146778..49147615
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_021159991.1 Reference GRCh38.p14 PATCHES

    Range
    72057..72894
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    49105671..49106503
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    GenBank, FASTA, Sequence Viewer (Graphics)