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LOC127402059 H3K4me1 hESC enhancer GRCh37_chr4:185938894-185939474 [ Homo sapiens (human) ]

Gene ID: 127402059, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127402059
Gene description
H3K4me1 hESC enhancer GRCh37_chr4:185938894-185939474
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127402059 in Genome Data Viewer
Location:
chromosome: 4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (185017740..185018320)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (188361153..188361733)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (185938894..185939474)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 4878 Neighboring gene microRNA 4455 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:185878684-185878847 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:185882462-185882962 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:185882963-185883463 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:185886653-185887153 Neighboring gene Sharpr-MPRA regulatory region 11336 Neighboring gene long intergenic non-protein coding RNA 2437 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22245 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:185939475-185940053 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:185940054-185940633 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:185941348-185942275 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:185942276-185943202 Neighboring gene helt bHLH transcription factor Neighboring gene long intergenic non-protein coding RNA 2436 Neighboring gene uncharacterized LOC105377588

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_104018.1 

    Range
    101..681
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    185017740..185018320
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    188361153..188361733
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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