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LOC127409134 NANOG hESC enhancer GRCh37_chr7:48356224-48356728 [ Homo sapiens (human) ]

Gene ID: 127409134, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127409134
Gene description
NANOG hESC enhancer GRCh37_chr7:48356224-48356728
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127409134 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (48316627..48317131)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (48479331..48479835)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (48356224..48356728)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18172 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:48127865-48128394 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:48128927-48129456 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:48145170-48145393 Neighboring gene uncharacterized LOC105375271 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:48172671-48173278 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:48186209-48186849 Neighboring gene uridine phosphorylase 1 Neighboring gene NANOG hESC enhancer GRCh37_chr7:48217687-48218188 Neighboring gene ATP binding cassette subfamily A member 13 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:48284398-48285597 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr7:48337872-48339071 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18174 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:48361367-48361866 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr7:48576772-48577971 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:48646747-48647247 Neighboring gene uncharacterized LOC105375272 Neighboring gene long intergenic non-protein coding RNA 2838

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_111099.1 

    Range
    101..605
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    48316627..48317131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    48479331..48479835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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