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LOC127458452 H3K4me1 hESC enhancer GRCh37_chr8:1534609-1535108 [ Homo sapiens (human) ]

Gene ID: 127458452, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127458452
Gene description
H3K4me1 hESC enhancer GRCh37_chr8:1534609-1535108
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127458452 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (1586443..1586942)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (1365437..1365936)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (1534609..1535108)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene DLG associated protein 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1321423-1321923 Neighboring gene keratinocyte proline-rich protein-like Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr8:1322036-1322849 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1325138-1326080 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:1365595-1365747 Neighboring gene uncharacterized LOC105377775 Neighboring gene uncharacterized LOC105379586 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:1385309-1385823 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:1403885-1405084 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1427697-1428250 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1449675-1450203 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1455237-1455738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1455739-1456238 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1487477-1487978 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1487979-1488478 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1525979-1526505 Neighboring gene DLGAP2 antisense RNA 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:1552920-1554119 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:1555917-1556470 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1574652-1575623 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:1580608-1581807 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:1585200-1585433 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:1605998-1606719 Neighboring gene uncharacterized LOC124901870 Neighboring gene conserved acetylation island sequence 7 enhancer Neighboring gene DNA fragmentation factor subunit alpha pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_113225.1 

    Range
    101..600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    1586443..1586942
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187654.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    196059..196558
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    1365437..1365936
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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