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LOC127460636 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:143255826-143256368 [ Homo sapiens (human) ]

Gene ID: 127460636, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127460636
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:143255826-143256368
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127460636 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (142174465..142175007)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (143312270..143312812)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (143255826..143256368)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene DNAJC8 pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143071812-143072312 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143072313-143072813 Neighboring gene uncharacterized LOC124902047 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:143101785-143102466 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:143102467-143103146 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28056 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr8:143111623-143112363 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143115683-143116183 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:143123379-143124338 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143144129-143144846 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143157259-143157760 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143177621-143178219 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:143211431-143211948 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:143211949-143212465 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:143212466-143212982 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143214353-143214914 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143226568-143227481 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143240023-143240524 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:143252084-143252984 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:143255282-143255825 Neighboring gene uncharacterized LOC105375792 Neighboring gene microRNA 4472-1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_115405.1 

    Range
    101..643
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    142174465..142175007
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    143312270..143312812
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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