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LOC127817037 H3K4me1 hESC enhancer GRCh37_chr10:1449419-1450003 [ Homo sapiens (human) ]

Gene ID: 127817037, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127817037
Gene description
H3K4me1 hESC enhancer GRCh37_chr10:1449419-1450003
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127817037 in Genome Data Viewer
Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (1407224..1407808)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (1406188..1406772)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (1449419..1450003)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1219106-1219608 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1230396-1230996 Neighboring gene long intergenic non-protein coding RNA 200 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:1234984-1236183 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1237029-1237528 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1256314-1256814 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1258172-1258702 Neighboring gene adenosine deaminase RNA specific B2 (inactive) Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1283673-1284184 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1284185-1284695 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:1297166-1297666 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:1297667-1298167 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1312697-1313582 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1313583-1314467 Neighboring gene MPRA-validated peak840 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1315089-1315589 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1334566-1335464 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1335779-1336688 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1352351-1352995 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1351707-1352350 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1352996-1353639 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1354285-1354928 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1354929-1355573 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1386449-1387132 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2901 Neighboring gene uncharacterized LOC105376342 Neighboring gene Sharpr-MPRA regulatory region 10920 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1421674-1422378 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1422379-1423081 Neighboring gene NANOG hESC enhancer GRCh37_chr10:1423311-1423822 Neighboring gene uncharacterized LOC124902364 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:1451683-1452882 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1476825-1477620 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1477621-1478414 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:1501805-1503004 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1507617-1508326 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1516725-1517244 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1517245-1517763 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2902 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:1531466-1531632 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:1541598-1542797 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1564309-1564810 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1571713-1572712 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:1576761-1577960 Neighboring gene ADARB2 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1594399-1594926 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1601202-1601702 Neighboring gene Sharpr-MPRA regulatory region 9114 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1644395-1644901 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1651053-1651582 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1651583-1652110 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:1652312-1652473 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1669763-1670264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1670265-1670764 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1701309-1701862 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1701863-1702414 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1704841-1705340 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1712437-1712938 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1712939-1713438 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2903 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1721606-1722106 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1722107-1722607 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:1737450-1737614 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2904 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1779051-1779647 Neighboring gene uncharacterized LOC105376345 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:1789244-1790443

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_118520.1 

    Range
    101..685
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    1407224..1407808
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    1406188..1406772
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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