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LOC127818761 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:93682269-93682802 [ Homo sapiens (human) ]

Gene ID: 127818761, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127818761
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:93682269-93682802
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127818761 in Genome Data Viewer
Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (91922512..91923045)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (92804622..92805155)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (93682269..93682802)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene NANOG hESC enhancer GRCh37_chr10:93580083-93580584 Neighboring gene tankyrase 2 Neighboring gene signal recognition particle 9 pseudogene 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:93640869-93641370 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:93641371-93641870 Neighboring gene Sharpr-MPRA regulatory region 9903 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2611 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3765 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3766 Neighboring gene fibroblast growth factor binding protein 3 Neighboring gene B-TFIID TATA-box binding protein associated factor 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:93805711-93806387 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:93816841-93817342 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:93835428-93836089 Neighboring gene cytoplasmic polyadenylation element binding protein 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3767 Neighboring gene uncharacterized LOC107984254

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_120233.1 

    Range
    101..634
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    91922512..91923045
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    92804622..92805155
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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