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LOC127820892 H3K4me1 hESC enhancer GRCh37_chr11:44914725-44915296 [ Homo sapiens (human) ]

Gene ID: 127820892, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127820892
Gene description
H3K4me1 hESC enhancer GRCh37_chr11:44914725-44915296
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127820892 in Genome Data Viewer
Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (44893174..44893745)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (45050020..45050591)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (44914725..44915296)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:44710524-44711057 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44713680-44714180 Neighboring gene long intergenic non-protein coding RNA 2704 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:44729901-44731100 Neighboring gene Sharpr-MPRA regulatory region 8672 Neighboring gene TSPAN18 antisense RNA 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44747040-44747900 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44747901-44748762 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3279 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:44750014-44750516 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:44750517-44751017 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44763637-44764332 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44764333-44765028 Neighboring gene tetraspanin 18 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44770929-44771430 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44774444-44775252 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44775253-44776059 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44787811-44788311 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44795688-44796462 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44798427-44798928 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44798929-44799428 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21411 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44806959-44807560 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44807561-44808160 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44816852-44817768 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:44819455-44820133 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21423 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44844210-44845075 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44845076-44845940 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44845941-44846806 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21436 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21440 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21441 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21442 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44869391-44869986 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44870581-44871176 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44871177-44871770 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_21450 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44878622-44879400 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44883049-44883676 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44883677-44884304 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4663 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44907116-44907616 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44907617-44908117 Neighboring gene uncharacterized LOC124902664 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44932558-44933414 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4664 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44944349-44944850 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:44952242-44952850 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44957874-44958474 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44960045-44960758 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44964865-44965513 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:44966723-44967326 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3281 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3282 Neighboring gene tumor protein p53 inducible protein 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_122350.1 

    Range
    101..672
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    44893174..44893745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    45050020..45050591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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