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LOC127821197 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61483273-61484058 [ Homo sapiens (human) ]

Gene ID: 127821197, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127821197
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61483273-61484058
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127821197 in Genome Data Viewer
Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (61715801..61716586)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (61704721..61705507)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (61483273..61484058)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61355975-61356553 Neighboring gene uncharacterized LOC101927495 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61366831-61367498 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61368167-61368834 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61393636-61394198 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61394199-61394759 Neighboring gene Sharpr-MPRA regulatory region 3465 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61396115-61397096 Neighboring gene ribosomal protein lateral stalk subunit P0 pseudogene 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61406067-61406567 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:61406607-61407134 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:61408188-61408713 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:61430561-61431253 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61450060-61450734 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61450735-61451408 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61457781-61458312 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61458313-61458844 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61462250-61462775 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61462776-61463302 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61463303-61463829 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61465411-61465936 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61465937-61466463 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61466990-61467516 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61467517-61468042 Neighboring gene diacylglycerol lipase alpha Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61468570-61469095 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61482486-61483272 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61484845-61485630 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61485631-61486417 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61486418-61487203 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61487991-61488775 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61507907-61508480 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61514637-61515498 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61516359-61517220 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3397 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3398 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:61523524-61524723 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61524877-61525520 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61528511-61529267 Neighboring gene MYRF antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61535574-61536150 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:61536151-61536726 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4800 Neighboring gene myelin regulatory factor Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61546818-61547486 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61548157-61548825 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61552558-61553302 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:61553303-61554047 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancers GRCh37_chr11:61559319-61560296 and GRCh37_chr11:61560297-61561272 Neighboring gene transmembrane protein 258 Neighboring gene microRNA 611

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_122649.1 

    Range
    101..886
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    61715801..61716586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    61704721..61705507
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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