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LOC127821517 H3K4me1 hESC enhancer GRCh37_chr11:65733572-65734072 [ Homo sapiens (human) ]

Gene ID: 127821517, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127821517
Gene description
H3K4me1 hESC enhancer GRCh37_chr11:65733572-65734072
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127821517 in Genome Data Viewer
Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (65966101..65966601)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (65959182..65959682)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (65733572..65734072)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr11:65685650-65686569 and GRCh37_chr11:65686570-65687490 Neighboring gene DR1 associated protein 1 Neighboring gene CRISPRi-validated cis-regulatory element chr11.3343 Neighboring gene NANOG hESC enhancer GRCh37_chr11:65704708-65705232 Neighboring gene uncharacterized LOC105369350 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:65708489-65708988 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:65708959-65709182 Neighboring gene testis specific 10 interacting protein Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:65729063-65729850 Neighboring gene spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP Neighboring gene phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5024 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:65767725-65768224 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5025 Neighboring gene eukaryotic translation initiation factor 1A domain containing Neighboring gene barrier to autointegration nuclear assembly factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_122966.1 

    Range
    101..601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    65966101..65966601
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    65959182..65959682
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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