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LOC127825683 NANOG hESC enhancer GRCh37_chr12:130560143-130560670 [ Homo sapiens (human) ]

Gene ID: 127825683, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127825683
Gene description
NANOG hESC enhancer GRCh37_chr12:130560143-130560670
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127825683 in Genome Data Viewer
Location:
chromosome: 12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (130075598..130076125)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (130112746..130113273)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (130560143..130560670)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370077 Neighboring gene long intergenic non-protein coding RNA 2419 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:130571983-130572500 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:130572501-130573018 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:130597592-130598092 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:130615286-130615803 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:130615804-130616320 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:130616321-130616838 Neighboring gene uncharacterized LOC124903088 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_25699 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_25704 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_25722 Neighboring gene FZD10 antisense divergent transcript Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:130645489-130646055 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:130646056-130646622

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_127195.1 

    Range
    101..628
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    130075598..130076125
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    130112746..130113273
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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