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LOC127827420 NANOG hESC enhancer GRCh37_chr14:37274394-37274895 [ Homo sapiens (human) ]

Gene ID: 127827420, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127827420
Gene description
NANOG hESC enhancer GRCh37_chr14:37274394-37274895
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127827420 in Genome Data Viewer
Location:
chromosome: 14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (36805189..36805690)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (30994639..30995140)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (37274394..37274895)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene RN7SK pseudogene 257 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:37116557-37117386 Neighboring gene uncharacterized LOC105370455 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:37123150-37123888 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8284 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:37125365-37126102 Neighboring gene PAX9 promoter region Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:37131533-37132044 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:37132045-37132554 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:37132555-37133065 Neighboring gene NANOG hESC enhancer GRCh37_chr14:37153788-37154289 Neighboring gene solute carrier family 25 member 21 Neighboring gene paired box 9 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr14:37271122-37272321 Neighboring gene uncharacterized LOC107984668 Neighboring gene microRNA 4503

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_128924.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    36805189..36805690
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    30994639..30995140
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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