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LOC127827972 H3K4me1 hESC enhancer GRCh37_chr14:74825115-74825693 [ Homo sapiens (human) ]

Gene ID: 127827972, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127827972
Gene description
H3K4me1 hESC enhancer GRCh37_chr14:74825115-74825693
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127827972 in Genome Data Viewer
Location:
chromosome: 14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (74358412..74358990)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (68566292..68566870)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (74825115..74825693)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74758461-74759313 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5929 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8726 Neighboring gene ATP binding cassette subfamily D member 4 Neighboring gene SUB1 pseudogene 2 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74792429-74793048 Neighboring gene vertebrae development associated Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74794289-74794910 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:74796151-74796770 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74815437-74816187 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74816188-74816937 Neighboring gene ribosomal protein S2 pseudogene 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:74861891-74862391 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:74868255-74869164 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:74873841-74874342 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:74876293-74876840 Neighboring gene synapse differentiation inducing 1 like Neighboring gene microRNA 4709 Neighboring gene NPC intracellular cholesterol transporter 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_129471.1 

    Range
    101..679
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    74358412..74358990
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    68566292..68566870
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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