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LOC127829267 NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:40178335-40178866 [ Homo sapiens (human) ]

Gene ID: 127829267, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127829267
Gene description
NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:40178335-40178866
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127829267 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (39886134..39886665)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (37691349..37691880)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (40178335..40178866)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370785 Neighboring gene fibrous sheath interacting protein 1 Neighboring gene NANOG hESC enhancer GRCh37_chr15:39958804-39959320 Neighboring gene Sharpr-MPRA regulatory region 4200 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6312 Neighboring gene uncharacterized LOC105370941 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9217 Neighboring gene G protein-coupled receptor 176 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:40176182-40176852 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:40176853-40177522 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:40177802-40178334 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:40179399-40179929 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:40186807-40187332 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40200676-40201176 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:40209802-40209908 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:40211506-40212311 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6313 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9218 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6314 Neighboring gene GPR176 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9219 Neighboring gene small nucleolar RNA U13 Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_130749.1 

    Range
    101..632
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    39886134..39886665
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    37691349..37691880
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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