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LOC127889452 H3K4me1 hESC enhancer GRCh37_chr18:56886610-56887224 [ Homo sapiens (human) ]

Gene ID: 127889452, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127889452
Gene description
H3K4me1 hESC enhancer GRCh37_chr18:56886610-56887224
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127889452 in Genome Data Viewer
Location:
chromosome: 18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (59219378..59219992)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (59420640..59421254)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (56886610..56887224)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9491 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13410 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13411 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13412 Neighboring gene SEC11 homolog C, signal peptidase complex subunit Neighboring gene signal recognition particle 19kDa pseudogene Neighboring gene MED14-independent group 3 enhancer GRCh37_chr18:56855703-56856902 Neighboring gene MPRA-validated peak3170 silencer Neighboring gene gastrin releasing peptide Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:56936011-56936521 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9492 Neighboring gene retina and anterior neural fold homeobox Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9493 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9494 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9495 Neighboring gene Sharpr-MPRA regulatory region 1890 Neighboring gene complexin 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_138981.1 

    Range
    101..715
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    59219378..59219992
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    59420640..59421254
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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