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LOC127892688 H3K27ac hESC enhancer GRCh37_chr20:18477654-18478218 [ Homo sapiens (human) ]

Gene ID: 127892688, updated on 12-Sep-2024

Summary

Gene symbol
LOC127892688
Gene description
H3K27ac hESC enhancer GRCh37_chr20:18477654-18478218
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region includes an enhancer that was validated by the ChIP-STARR-seq massively parallel reporter assay (MPRA) in naive human embryonic stem cells, where it is marked by the H3K27ac histone modification. This locus also includes three accessible chromatin subregions that were validated as enhancers based on their ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) MPRA in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

See LOC127892688 in Genome Data Viewer
Location:
chromosome: 20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (18496998..18497574)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (18548124..18548700)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (18477642..18478218)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene RNA polymerase III subunit F Neighboring gene microRNA 3192 Neighboring gene ribosomal protein L21 pseudogene 3 Neighboring gene RB binding protein 9, serine hydrolase Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17586 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17590 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17591 Neighboring gene ribosomal protein S19 pseudogene 1 Neighboring gene SEC23 homolog B, COPII coat complex component Neighboring gene MED14-independent group 3 enhancer GRCh37_chr20:18504796-18505995

Genomic regions, transcripts, and products

General gene information

Other Names

  • ATAC-STARR-seq lymphoblastoid active region 17587
  • ATAC-STARR-seq lymphoblastoid active region 17588
  • ATAC-STARR-seq lymphoblastoid active region 17589

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_142479.2 

    Range
    101..677
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    18496998..18497574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    18548124..18548700
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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