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MIURF mitochondrial elongation factor 1 upstream open reading frame [ Homo sapiens (human) ]

Gene ID: 127898561, updated on 27-Nov-2024

Summary

Gene symbol
MIURF
Gene description
mitochondrial elongation factor 1 upstream open reading frame
See related
Ensembl:ENSG00000285025
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIEF1; AltMIEF1; AltMiD51; MIEF1-MP
Summary
This gene represents an upstream open reading frame located in the transcripts of mitochondrial elongation factor 1 (GeneID:) gene. The open reading frame shows a strong signature of protein-coding regions in PhyloCSF and translation of the 70aa protein is supported by peptide and ribosome profiling data. [provided by RefSeq, Dec 2022]
Orthologs
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Genomic context

See MIURF in Genome Data Viewer
Location:
22q13.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (39504231..39504443)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (39974860..39975072)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (39900236..39900448)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:39874451-39874952 Neighboring gene MGAT3 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 8945 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13755 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13756 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:39891955-39892455 Neighboring gene uncharacterized LOC105373035 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:39898075-39898576 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:39898577-39899076 Neighboring gene mitochondrial elongation factor 1 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr22:39906581-39907106 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13758 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19058 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19059 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19060 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:39919051-39919552 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19061 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19062 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19063 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19064 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19065 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19066 Neighboring gene activating transcription factor 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19067 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19068 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:39927967-39928482 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:39928483-39928998 Neighboring gene ribosomal protein S19 binding protein 1

Genomic regions, transcripts, and products

General protein information

Preferred Names
mitochondrial ribosome and complex I assembly factor AltMIEF1
Names
MIEF1 microprotein
alternative MIEF1 protein
alternative transcript upstream of MiD51

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001414695.1NP_001401624.1  mitochondrial ribosome and complex I assembly factor AltMIEF1

    Status: VALIDATED

    Source sequence(s)
    AL022312
    UniProtKB/Swiss-Prot
    L0R8F8
    Related
    ENSP00000490747.1, ENST00000637854.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    39504231..39504443
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    39974860..39975072
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)