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CG43089 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 12798588, updated on 4-Jan-2025

Summary

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Official Symbol
CG43089provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0262535
Locus tag
Dmel_CG43089
See related
AllianceGenome:FB:FBgn0262535
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG43089; lincRNA.427
Summary
Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG43089 in Genome Data Viewer
Location:
63E8-63E8; 3-8 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3714027..3714717)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3714027..3714717)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43485 Neighboring gene long non-coding RNA:CR45675 Neighboring gene uncharacterized protein Neighboring gene pickpocket 27 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article
  2. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
  3. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article
  4. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article
  5. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cullin family protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG43089-PB
CG43089-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3714027..3714717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300001.1 → NP_001286930.1  uncharacterized protein Dmel_CG43089, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286930.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F3YDE8, M9ND39
    Conserved Domains (2) summary
    pfam01466
    Location:95 → 139
    Skp1; Skp1 family, dimerization domain
    cl02518
    Location:9 → 111
    BTB; BTB/POZ domain

  2. NM_001259677.1 → NP_001246606.1  uncharacterized protein Dmel_CG43089, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246606.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F3YDE8, M9ND39
    Conserved Domains (2) summary
    pfam01466
    Location:95 → 139
    Skp1; Skp1 family, dimerization domain
    cl02518
    Location:9 → 111
    BTB; BTB/POZ domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9ND39 M9ND39

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