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BRCA1 BRCA1 DNA repair associated [ Symphalangus syndactylus (siamang) ]

Gene ID: 129469801, updated on 18-Jul-2024

Summary

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Gene symbol
BRCA1
Gene description
BRCA1 DNA repair associated
Gene type
protein coding
RefSeq status
MODEL
Organism
Symphalangus syndactylus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Symphalangus
Orthologs
human mouse all
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Genomic context

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See BRCA1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2024_07 current NHGRI_mSymSyn1-v2.1_pri (GCF_028878055.3) 20 NC_072442.2 (43638390..43740904, complement)
RS_2023_03 previous assembly NHGRI_mSymSyn1-v1.1-hic.freeze_pri (GCF_028878055.1) 20 NC_072442.1 (49718645..49807535, complement)

Chromosome 20 - NC_072442.2Genomic Context describing neighboring genes Neighboring gene vesicle amine transport 1 Neighboring gene Rho family GTPase 2 Neighboring gene ADP-ribosylation factor-like protein 17 Neighboring gene NBR1 autophagy cargo receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evidence of a warfarin-sensitive cancer procoagulant in V2 carcinoma. Roncaglioni MC, et al. Haematologica, 1989 Mar-Apr. PMID 2501168
  2. Rapid evolution of BRCA1 and BRCA2 in humans and other primates. Lou DI, et al. BMC Evol Biol, 2014 Jul 11. PMID 25011685, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chordate embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dosage compensation by inactivation of X chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of BRCA1-A complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of BRCA1-BARD1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breast cancer type 1 susceptibility protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028878055.3-RS_2024_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mSymSyn1-v2.1_pri Primary Assembly

Genomic

  1. NC_072442.2 Reference NHGRI_mSymSyn1-v2.1_pri Primary Assembly

    Range
    43638390..43740904 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063629056.1 → XP_063485126.1  breast cancer type 1 susceptibility protein isoform X8

  2. XM_063629051.1 → XP_063485121.1  breast cancer type 1 susceptibility protein isoform X3

  3. XM_063629046.1 → XP_063485116.1  breast cancer type 1 susceptibility protein isoform X2

  4. XM_063629048.1 → XP_063485118.1  breast cancer type 1 susceptibility protein isoform X2

  5. XM_063629081.1 → XP_063485151.1  breast cancer type 1 susceptibility protein isoform X24

  6. XM_063629076.1 → XP_063485146.1  breast cancer type 1 susceptibility protein isoform X20

  7. XM_063629070.1 → XP_063485140.1  breast cancer type 1 susceptibility protein isoform X19

  8. XM_063629071.1 → XP_063485141.1  breast cancer type 1 susceptibility protein isoform X19

  9. XM_063629078.1 → XP_063485148.1  breast cancer type 1 susceptibility protein isoform X21

  10. XM_063629067.1 → XP_063485137.1  breast cancer type 1 susceptibility protein isoform X19

  11. XM_063629055.1 → XP_063485125.1  breast cancer type 1 susceptibility protein isoform X7

  12. XM_063629061.1 → XP_063485131.1  breast cancer type 1 susceptibility protein isoform X13

  13. XM_063629060.1 → XP_063485130.1  breast cancer type 1 susceptibility protein isoform X12

  14. XM_063629059.1 → XP_063485129.1  breast cancer type 1 susceptibility protein isoform X11

  15. XM_063629057.1 → XP_063485127.1  breast cancer type 1 susceptibility protein isoform X9

  16. XM_063629062.1 → XP_063485132.1  breast cancer type 1 susceptibility protein isoform X14

  17. XM_063629052.1 → XP_063485122.1  breast cancer type 1 susceptibility protein isoform X5

  18. XM_063629049.1 → XP_063485119.1  breast cancer type 1 susceptibility protein isoform X3

  19. XM_055256863.2 → XP_055112838.2  breast cancer type 1 susceptibility protein isoform X7

  20. XM_055256862.2 → XP_055112837.2  breast cancer type 1 susceptibility protein isoform X6

  21. XM_055256857.2 → XP_055112832.2  breast cancer type 1 susceptibility protein isoform X1

  22. XM_063629054.1 → XP_063485124.1  breast cancer type 1 susceptibility protein isoform X7

  23. XM_063629053.1 → XP_063485123.1  breast cancer type 1 susceptibility protein isoform X6

  24. XM_063629050.1 → XP_063485120.1  breast cancer type 1 susceptibility protein isoform X4

  25. XM_063629058.1 → XP_063485128.1  breast cancer type 1 susceptibility protein isoform X10

  26. XM_063629047.1 → XP_063485117.1  breast cancer type 1 susceptibility protein isoform X2

  27. XM_063629063.1 → XP_063485133.1  breast cancer type 1 susceptibility protein isoform X16

  28. XM_063629065.1 → XP_063485135.1  breast cancer type 1 susceptibility protein isoform X18

  29. XM_055256881.2 → XP_055112856.2  breast cancer type 1 susceptibility protein isoform X15

  30. XM_063629064.1 → XP_063485134.1  breast cancer type 1 susceptibility protein isoform X17

  31. XM_063629086.1 → XP_063485156.1  breast cancer type 1 susceptibility protein isoform X29

  32. XM_063629083.1 → XP_063485153.1  breast cancer type 1 susceptibility protein isoform X25

  33. XM_063629087.1 → XP_063485157.1  breast cancer type 1 susceptibility protein isoform X30

  34. XM_063629082.1 → XP_063485152.1  breast cancer type 1 susceptibility protein isoform X24

  35. XM_063629080.1 → XP_063485150.1  breast cancer type 1 susceptibility protein isoform X23

  36. XM_063629075.1 → XP_063485145.1  breast cancer type 1 susceptibility protein isoform X20

  37. XM_055256885.2 → XP_055112860.2  breast cancer type 1 susceptibility protein isoform X22

  38. XM_063629077.1 → XP_063485147.1  breast cancer type 1 susceptibility protein isoform X22

  39. XM_063629079.1 → XP_063485149.1  breast cancer type 1 susceptibility protein isoform X21

  40. XM_063629084.1 → XP_063485154.1  breast cancer type 1 susceptibility protein isoform X27

  41. XM_063629074.1 → XP_063485144.1  breast cancer type 1 susceptibility protein isoform X21

  42. XM_055256884.2 → XP_055112859.2  breast cancer type 1 susceptibility protein isoform X20

  43. XM_063629073.1 → XP_063485143.1  breast cancer type 1 susceptibility protein isoform X20

  44. XM_063629069.1 → XP_063485139.1  breast cancer type 1 susceptibility protein isoform X19

  45. XM_063629072.1 → XP_063485142.1  breast cancer type 1 susceptibility protein isoform X20

  46. XM_063629068.1 → XP_063485138.1  breast cancer type 1 susceptibility protein isoform X19

  47. XM_055256891.2 → XP_055112866.2  breast cancer type 1 susceptibility protein isoform X26

  48. XM_063629066.1 → XP_063485136.1  breast cancer type 1 susceptibility protein isoform X19

  49. XM_055256882.2 → XP_055112857.2  breast cancer type 1 susceptibility protein isoform X19

  50. XM_063629085.1 → XP_063485155.1  breast cancer type 1 susceptibility protein isoform X28

Nucleotide Protein
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