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LOC129660706 ReSE screen-validated silencer GRCh37_chr2:65131242-65131436 [ Homo sapiens (human) ]

Gene ID: 129660706, updated on 12-Sep-2024

Summary

Gene symbol
LOC129660706
Gene description
ReSE screen-validated silencer GRCh37_chr2:65131242-65131436
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region used in a lentiviral ReSE (repressive ability of silencer elements) screen that assays for cell survival based on transcriptional repression of an apoptosis-inducing fusion protein. This region was identified as a functional silencer in phorbol 12-myristate 13-acetate-treated (for megakaryocytic differentiation) K562 erythroleukemia cells. [provided by RefSeq, Apr 2023]
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Genomic context

See LOC129660706 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (64904108..64904302)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (64913725..64913918)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (65131242..65131436)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 341, pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:65058033-65059232 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:65065480-65066679 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15909 Neighboring gene long intergenic non-protein coding RNA 1800 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15910 Neighboring gene Sharpr-MPRA regulatory region 2197 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:65087040-65087243 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15911 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11569 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:65103167-65103373 Neighboring gene Sharpr-MPRA regulatory region 15627 Neighboring gene long intergenic non-protein coding RNA 2245 Neighboring gene small nucleolar RNA U13 Neighboring gene RNA, 7SL, cytoplasmic 211, pseudogene

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_157743.1 

    Range
    101..295
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    64904108..64904302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    64913725..64913918
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    GenBank, FASTA, Sequence Viewer (Graphics)