U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC129661966 ReSE screen-validated silencer GRCh37_chr7:40095303-40095542 [ Homo sapiens (human) ]

Gene ID: 129661966, updated on 12-Sep-2024

Summary

Go to the top of the page Help
Gene symbol
LOC129661966
Gene description
ReSE screen-validated silencer GRCh37_chr7:40095303-40095542
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region used in a lentiviral ReSE (repressive ability of silencer elements) screen that assays for cell survival based on transcriptional repression of an apoptosis-inducing fusion protein. This region was identified as a functional silencer in HepG2 liver carcinoma cells. [provided by RefSeq, Apr 2023]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LOC129661966 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (40055704..40055943)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (40213153..40213392)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (40095303..40095542)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928688 Neighboring gene RNA, 7SL, cytoplasmic 496, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:39954013-39954514 Neighboring gene Sharpr-MPRA regulatory region 5390 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25884 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:39988304-39989223 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:39989224-39990142 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18115 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18116 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:39991063-39991981 Neighboring gene CDK13 divergent transcript Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:40015128-40015628 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:40017861-40018605 Neighboring gene cyclin dependent kinase 13 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25889 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18117 Neighboring gene HIG1 hypoxia inducible domain family member 1A pseudogene 7 Neighboring gene M-phase specific PLK1 interacting protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Systematic identification of silencers in human cells. Pang B, et al. Nat Genet, 2020 Mar. PMID 32094911, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_159002.1 

    Range
    101..340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    40055704..40055943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    40213153..40213392
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases