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LOC129663772 ReSE screen-validated silencer GRCh37_chr16:15929109-15929286 [ Homo sapiens (human) ]

Gene ID: 129663772, updated on 12-Sep-2024

Summary

Gene symbol
LOC129663772
Gene description
ReSE screen-validated silencer GRCh37_chr16:15929109-15929286
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region used in a lentiviral ReSE (repressive ability of silencer elements) screen that assays for cell survival based on transcriptional repression of an apoptosis-inducing fusion protein. This region was identified as a functional silencer in K562 erythroleukemia cells. [provided by RefSeq, Apr 2023]
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Genomic context

See LOC129663772 in Genome Data Viewer
Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (15835252..15835429)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (15840182..15840359)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (15929109..15929286)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene myosin heavy chain 11 Neighboring gene uncharacterized LOC124903650 Neighboring gene uncharacterized LOC124903651 Neighboring gene Sharpr-MPRA regulatory region 5546 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:15901002-15901817 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:15951931-15952432 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr16:15972689-15973888 Neighboring gene RNA, U6 small nuclear 213, pseudogene Neighboring gene centrosomal protein 20 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr16:15993095-15994294 Neighboring gene uncharacterized LOC107984869 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:16018443-16018944 Neighboring gene ribosomal protein L15 pseudogene 20

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_160778.1 

    Range
    101..278
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    15835252..15835429
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187607.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    1493242..1493419
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    15840182..15840359
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    GenBank, FASTA, Sequence Viewer (Graphics)