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LOC130000235 ATAC-STARR-seq lymphoblastoid active region 27254 [ Homo sapiens (human) ]

Gene ID: 130000235, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130000235
Gene description
ATAC-STARR-seq lymphoblastoid active region 27254
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130000235 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (38554351..38554440)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (38831343..38831432)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (38411869..38411958)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr8:38368263-38369061 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:38369732-38370310 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr8:38370311-38370888 Neighboring gene long intergenic non-protein coding RNA 3042 Neighboring gene OCT4 hESC enhancer GRCh37_chr8:38376955-38377456 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:38379090-38380048 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr8:38385147-38386346 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr8:38386932-38387753 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:38387754-38388574 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:38388575-38389395 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:38389396-38390215 Neighboring gene uncharacterized LOC124901935 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27253 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:38409783-38410284 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:38422268-38422787 Neighboring gene uncharacterized LOC105379384 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:38422788-38423306 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:38424551-38425084 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr8:38425085-38425618 Neighboring gene ring finger protein 5 pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_179681.1 

    Range
    101..190
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    38554351..38554440
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    38831343..38831432
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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