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C28G1.10 E2 ubiquitin-conjugating enzyme [ Caenorhabditis elegans ]

Gene ID: 13222010, updated on 9-Dec-2024

Summary

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Official Symbol
C28G1.10
Official Full Name
E2 ubiquitin-conjugating enzyme
Primary source
WormBase:WBGene00219376
Locus tag
CELE_C28G1.10
See related
AllianceGenome:WB:WBGene00219376
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C28G1.10 in Genome Data Viewer
Location:
chromosome: X
Exon count:
4
Sequence:
Chromosome: X; NC_003284.9 (8847122..8848482)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene tRNA-Gly Neighboring gene ncRNA Neighboring gene tRNA-Gly Neighboring gene C2H2-type domain-containing protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein modification by small protein conjugation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
E2 ubiquitin-conjugating enzyme
NP_001257066.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    8847122..8848482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001270137.5 → NP_001257066.1  E2 ubiquitin-conjugating enzyme [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257066.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H8W3X5
    Conserved Domains (1) summary
    cd00195
    Location:5 → 149
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
Nucleotide Protein
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