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LOC132255349 STARR-positive B cell enhancers ABC_E11715 and ABC_E10249 [ Mus musculus (house mouse) ]

Gene ID: 132255349, updated on 10-Feb-2024

Summary

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Gene symbol
LOC132255349
Gene description
STARR-positive B cell enhancers ABC_E11715 and ABC_E10249
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
This genomic region was identified as a putative B cell regulatory element by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing). Two subregions were validated as enhancers by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. [provided by RefSeq, Sep 2023]
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Genomic context

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See LOC132255349 in Genome Data Viewer
Location:
chromosome: 4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116646197..116646786)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene expressed sequence AV051173 Neighboring gene peroxiredoxin 1 Neighboring gene STARR-positive B cell enhancer ABC_E9593 Neighboring gene STARR-positive B cell enhancer ABC_E2706 Neighboring gene methylmalonic aciduria cblC type, with homocystinuria Neighboring gene coiled-coil domain containing 163 Neighboring gene STARR-positive B cell enhancer ABC_E37 Neighboring gene STARR-seq mESC enhancer starr_11147 Neighboring gene testis-specific kinase 2 Neighboring gene STARR-seq mESC enhancer starr_11148 Neighboring gene STARR-seq mESC enhancer starr_11149 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:116480418-116480527 Neighboring gene target of EGR1, member 1 (nuclear) Neighboring gene mutY DNA glycosylase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene regulatory networks STARR-ing B cells. Martínez de Paz A, et al. Nat Immunol, 2020 Feb. PMID 31873293, Free PMC Article
  2. Charting the cis-regulome of activated B cells by coupling structural and functional genomics. Chaudhri VK, et al. Nat Immunol, 2020 Feb. PMID 31873292

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • STARR-positive B cell enhancer ABC_E10249
  • STARR-positive B cell enhancer ABC_E11715

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_231584.1 

    Range
    101..690
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    116646197..116646786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version