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LOC132443375 STARR-positive B cell enhancer ABC_E5450 [ Mus musculus (house mouse) ]

Gene ID: 132443375, updated on 10-Feb-2024

Summary

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Gene symbol
LOC132443375
Gene description
STARR-positive B cell enhancer ABC_E5450
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
This genomic region was identified as a putative B cell regulatory element by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing), and was validated as an enhancer by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. [provided by RefSeq, Oct 2023]
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Genomic context

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See LOC132443375 in Genome Data Viewer
Location:
chromosome: 14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (66385073..66385374)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene a disintegrin and metallopeptidase domain 2 Neighboring gene translocase of inner mitochondrial membrane 23 homolog pseudogene Neighboring gene epoxide hydrolase 2, cytoplasmic Neighboring gene STARR-seq mESC enhancer starr_36988 Neighboring gene cholinergic receptor nicotinic alpha 2 subunit Neighboring gene PTK2 protein tyrosine kinase 2 beta Neighboring gene STARR-positive B cell enhancer ABC_E7326 Neighboring gene STARR-seq mESC enhancer starr_36992 Neighboring gene predicted gene, 52098 Neighboring gene STARR-positive B cell enhancer ABC_E3121 Neighboring gene STARR-seq mESC enhancer starr_36993 Neighboring gene STARR-seq mESC enhancer starr_36994 Neighboring gene predicted gene, 52099

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene regulatory networks STARR-ing B cells. Martínez de Paz A, et al. Nat Immunol, 2020 Feb. PMID 31873293, Free PMC Article
  2. Charting the cis-regulome of activated B cells by coupling structural and functional genomics. Chaudhri VK, et al. Nat Immunol, 2020 Feb. PMID 31873292

GeneRIFs: Gene References Into Functions

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_239797.1 

    Range
    101..402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    66385073..66385374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version