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LMXM_08_29_0820 CPC cysteine peptidase, Clan CA, family C1,Cathepsin B-like [ Leishmania mexicana MHOM/GT/2001/U1103 ]

Gene ID: 13447272, updated on 30-Oct-2024

Summary

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Gene symbol
LMXM_08_29_0820
Gene description
CPC cysteine peptidase, Clan CA, family C1,Cathepsin B-like
Locus tag
LMXM_08_29_0820
Gene type
protein coding
RNA name
CPC cysteine peptidase, Clan CA, family C1,Cathepsin B-like
RefSeq status
PROVISIONAL
Organism
Leishmania mexicana MHOM/GT/2001/U1103 (strain: MHOM/GT/2001/U1103)
Lineage
Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania
Orthologs
Leishmania major all
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Genomic context

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See LMXM_08_29_0820 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
1
Sequence:
Chromosome: 8; NC_018312.1 (848597..849619)

Chromosome 8 - NC_018312.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_018312.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cysteine Peptidase B Regulates Leishmania mexicana Virulence through the Modulation of GP63 Expression. Casgrain PA, et al. PLoS Pathog, 2016 May. PMID 27191844, Free PMC Article
  2. Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Rogers MB, et al. Genome Res, 2011 Dec. PMID 22038252, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Names
CPC cysteine peptidase, Clan CA, family C1,Cathepsin B-like
cysteine peptidase C (CPC)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_018312.1 Reference assembly

    Range
    848597..849619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003872430.1 → XP_003872479.1  CPC cysteine peptidase, Clan CA, family C1,Cathepsin B-like [Leishmania mexicana MHOM/GT/2001/U1103]

    See identical proteins and their annotated locations for XP_003872479.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    E9ALZ5, Q25319
    Conserved Domains (1) summary
    cd02620
    Location:99 → 335
    Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
Nucleotide Protein
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