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Epb41l2 erythrocyte membrane protein band 4.1 like 2 [ Mus musculus (house mouse) ]

Gene ID: 13822, updated on 27-Nov-2024

Summary

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Official Symbol
Epb41l2provided by MGI
Official Full Name
erythrocyte membrane protein band 4.1 like 2provided by MGI
Primary source
MGI:MGI:103009
See related
Ensembl:ENSMUSG00000019978 AllianceGenome:MGI:103009
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4.1G; NBL2; Epb4.1l2; D10Ertd398e
Summary
Enables PH domain binding activity and spectrin binding activity. Predicted to be involved in actomyosin structure organization and positive regulation of protein localization to cell cortex. Predicted to act upstream of or within actin cytoskeleton organization and regulation of cell shape. Predicted to be located in several cellular components, including actin cytoskeleton; cell cortex; and nucleoplasm. Predicted to be part of COP9 signalosome. Predicted to be active in cytoskeleton and plasma membrane. Is expressed in several structures, including bone; central nervous system; sensory organ; thymus; and urinary system. Orthologous to human EPB41L2 (erythrocyte membrane protein band 4.1 like 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in subcutaneous fat pad adult (RPKM 17.3), testis adult (RPKM 16.5) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Epb41l2 in Genome Data Viewer
Location:
10 A4; 10 12.26 cM
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (25235680..25399413)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (25359782..25523519)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene A kinase anchor protein 7 Neighboring gene predicted gene, 25016 Neighboring gene STARR-seq mESC enhancer starr_26098 Neighboring gene predicted gene, 40617 Neighboring gene STARR-seq mESC enhancer starr_26101 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:25123932-25124041 Neighboring gene predicted gene 29571 Neighboring gene small leucine-rich protein 1 Neighboring gene STARR-seq mESC enhancer starr_26106 Neighboring gene predicted gene, 36908

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Expression of protein 4.1G in Schwann cells of the peripheral nervous system. Ohno N, et al. J Neurosci Res, 2006 Aug 15. PMID 16752423
  2. The cytoskeletal adapter protein 4.1G organizes the internodes in peripheral myelinated nerves. Ivanovic A, et al. J Cell Biol, 2012 Feb 6. PMID 22291039, Free PMC Article
  3. Immunolocalization of membrane skeletal protein, 4.1G, in enteric glial cells in the mouse large intestine. Chen J, et al. Neurosci Lett, 2011 Jan 20. PMID 21093541
  4. Involvement of a membrane skeletal protein, 4.1G, for Sertoli/germ cell interaction. Terada N, et al. Reproduction, 2010 May. PMID 20200204
  5. Deficiency of a membrane skeletal protein, 4.1G, results in myelin abnormalities in the peripheral nervous system. Saitoh Y, et al. Histochem Cell Biol, 2017 Dec. PMID 28755316

See all (63) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cytoskeletal Protein 4.1G Is Essential for the Primary Ciliogenesis and Osteoblast Differentiation in Bone Formation.
    Title: Cytoskeletal Protein 4.1G Is Essential for the Primary Ciliogenesis and Osteoblast Differentiation in Bone Formation.
  2. The 4.1G functions as a signal for proper formation of myelin in peripheral nervous system.
    Title: Deficiency of a membrane skeletal protein, 4.1G, results in myelin abnormalities in the peripheral nervous system.
  3. 4.1G has a role in cell adhesion, spreading, and migration in MEF cells by modulating the surface expression of beta1 integrin and subsequent downstream signal transduction
    Title: Protein 4.1G Regulates Cell Adhesion, Spreading, and Migration of Mouse Embryonic Fibroblasts through the β1 Integrin Pathway.
  4. The findings indicate that the Src-MPP6-4.1G protein complex in Schmidt-Lanterman incisures(SLIs) has a role in signal transduction in the peripheral nervous system(PNS).
    Title: Involvement of Src in the membrane skeletal complex, MPP6-4.1G, in Schmidt-Lanterman incisures of mouse myelinated nerve fibers in PNS.
  5. 4.1G existed in an immunoprecipitable complex with spectrin and SERCA2.
    Title: Isoforms of protein 4.1 are differentially distributed in heart muscle cells: relation of 4.1R and 4.1G to components of the Ca2+ homeostasis system.
  6. protein 4.1G contributes to the organization of the internodal axolemma by targeting and/or maintaining glial transmembrane proteins along the axoglial interface
    Title: The cytoskeletal adapter protein 4.1G organizes the internodes in peripheral myelinated nerves.
  7. In the mouse sciatic nerve, protein 4.1G colocalized at Schmidt-Lanterman incisures (SLI) and the paranodes with a member of the membrane-associated guanylate kinase (MAGUK) family, membrane protein palmitoylated 6.
    Title: Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves.
  8. findings imply that 4.1G plays a role in spermatogenesis by mediating cell-cell adhesion between spermatogenic and Sertoli cells through its interaction with NECL4 on Sertoli cells
    Title: Lack of protein 4.1G causes altered expression and localization of the cell adhesion molecule nectin-like 4 in testis and can cause male infertility.
  9. 4.1G may have some roles in adhesion and/or signal transduction in unmylinated PNS nerve fibers
    Title: Immunolocalization of membrane skeletal protein, 4.1G, in enteric glial cells in the mouse large intestine.
  10. novel membrane skeletal protein, 4.1G, was found in germ cells, and considering its interaction with CADM family, it probably has roles in attachment of both Sertoli-germ and germ-germ cells
    Title: Involvement of a membrane skeletal protein, 4.1G, for Sertoli/germ cell interaction.
Submit: New GeneRIF Correction See all GeneRIFs (12)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables PH domain binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables actin binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables spectrin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables spectrin binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within actin cytoskeleton organization ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in actomyosin structure organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of protein localization to cell cortex ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of protein localization to cell cortex ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within regulation of cell shape ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
part_of COP9 signalosome IEA
Inferred from Electronic Annotation
more info
  
part_of COP9 signalosome ISO
Inferred from Sequence Orthology
more info
  
located_in actin cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in cell cortex ISO
Inferred from Sequence Orthology
more info
  
located_in cell cortex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cell junction IEA
Inferred from Electronic Annotation
more info
  
located_in cell junction ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
band 4.1-like protein 2
Names
erythrocyte membrane protein band 4.1-like 2 retinal
erythrocyte protein band 4.1 like 2
erythrocyte protein band 4.1l2 long
erythrocyte protein band 4.1l2 middle
generally expressed protein 4.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199265.2 → NP_001186194.1  band 4.1-like protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001186194.1

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274
    Consensus CDS
    CCDS23754.1
    UniProtKB/Swiss-Prot
    G3X9B8, O70318
    UniProtKB/TrEMBL
    Q80UE3
    Related
    ENSMUSP00000055122.9, ENSMUST00000053748.16
    Conserved Domains (7) summary
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    cd14473
    Location:302 → 394
    FERM_B-lobe; FERM domain B-lobe
    pfam04382
    Location:613 → 656
    SAB; SAB domain
    pfam05902
    Location:876 → 978
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 542
    FA; FERM adjacent (FA)
    pfam09379
    Location:215 → 278
    FERM_N; FERM N-terminal domain

  2. NM_001358751.2 → NP_001345680.1  band 4.1-like protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274
    Consensus CDS
    CCDS87973.1
    UniProtKB/TrEMBL
    Q3UNQ6, Q80UE3, Q80UE5
    Related
    ENSMUSP00000151685.2, ENSMUST00000218903.2
    Conserved Domains (5) summary
    PTZ00121
    Location:9 → 203
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:806 → 908
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  3. NM_001358753.2 → NP_001345682.1  band 4.1-like protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274
    UniProtKB/TrEMBL
    B6ZHC5
    Conserved Domains (5) summary
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:741 → 843
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 542
    FA; FERM adjacent (FA)
    cl26511
    Location:9 → 203
    Neuromodulin_N; Gap junction protein N-terminal region

  4. NM_001358754.2 → NP_001345683.1  band 4.1-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274
    Consensus CDS
    CCDS87972.1
    UniProtKB/TrEMBL
    B6ZHC5, Q80UE4
    Conserved Domains (5) summary
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:698 → 784
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 542
    FA; FERM adjacent (FA)
    cl26511
    Location:9 → 203
    Neuromodulin_N; Gap junction protein N-terminal region

  5. NM_001358755.2 → NP_001345684.1  band 4.1-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274
    UniProtKB/TrEMBL
    B6ZHC6, Q811B2
    Conserved Domains (5) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:595 → 679
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  6. NM_001404797.1 → NP_001391726.1  band 4.1-like protein 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274

  7. NM_001404798.1 → NP_001391727.1  band 4.1-like protein 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  8. NM_001404799.1 → NP_001391728.1  band 4.1-like protein 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  9. NM_001404801.1 → NP_001391730.1  band 4.1-like protein 2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274

  10. NM_001404802.1 → NP_001391731.1  band 4.1-like protein 2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  11. NM_001404803.1 → NP_001391732.1  band 4.1-like protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE5

  12. NM_001404805.1 → NP_001391734.1  band 4.1-like protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE5

  13. NM_001404806.1 → NP_001391735.1  band 4.1-like protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE5

  14. NM_001404807.1 → NP_001391736.1  band 4.1-like protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE5

  15. NM_001404808.1 → NP_001391737.1  band 4.1-like protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE5

  16. NM_001404809.1 → NP_001391738.1  band 4.1-like protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE5

  17. NM_001404810.1 → NP_001391739.1  band 4.1-like protein 2 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  18. NM_001404811.1 → NP_001391740.1  band 4.1-like protein 2 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274

  19. NM_001404812.1 → NP_001391741.1  band 4.1-like protein 2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274

  20. NM_001404813.1 → NP_001391742.1  band 4.1-like protein 2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  21. NM_001404815.1 → NP_001391744.1  band 4.1-like protein 2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  22. NM_001404816.1 → NP_001391745.1  band 4.1-like protein 2 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274

  23. NM_001404818.1 → NP_001391747.1  band 4.1-like protein 2 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  24. NM_001404819.1 → NP_001391748.1  band 4.1-like protein 2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274

  25. NM_001404828.1 → NP_001391757.1  band 4.1-like protein 2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  26. NM_001404829.1 → NP_001391758.1  band 4.1-like protein 2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  27. NM_001404830.1 → NP_001391759.1  band 4.1-like protein 2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  28. NM_001404831.1 → NP_001391760.1  band 4.1-like protein 2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  29. NM_001404832.1 → NP_001391761.1  band 4.1-like protein 2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  30. NM_001404833.1 → NP_001391762.1  band 4.1-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE4

  31. NM_001404834.1 → NP_001391763.1  band 4.1-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE4

  32. NM_001404835.1 → NP_001391764.1  band 4.1-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE4
    Related
    ENSMUSP00000151875.2, ENSMUST00000217929.2

  33. NM_001404837.1 → NP_001391766.1  band 4.1-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE4

  34. NM_001404838.1 → NP_001391767.1  band 4.1-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE4

  35. NM_001404839.1 → NP_001391768.1  band 4.1-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE4

  36. NM_001404840.1 → NP_001391769.1  band 4.1-like protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q80UE4

  37. NM_001404841.1 → NP_001391770.1  band 4.1-like protein 2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  38. NM_001404842.1 → NP_001391771.1  band 4.1-like protein 2 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  39. NM_001404843.1 → NP_001391772.1  band 4.1-like protein 2 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274

  40. NM_001404844.1 → NP_001391773.1  band 4.1-like protein 2 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  41. NM_001404845.1 → NP_001391774.1  band 4.1-like protein 2 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  42. NM_001404846.1 → NP_001391775.1  band 4.1-like protein 2 isoform 20

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  43. NM_001404847.1 → NP_001391776.1  band 4.1-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q811B2

  44. NM_001404848.1 → NP_001391777.1  band 4.1-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q811B2

  45. NM_001404849.1 → NP_001391778.1  band 4.1-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q811B2

  46. NM_001404850.1 → NP_001391779.1  band 4.1-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q811B2

  47. NM_001404851.1 → NP_001391780.1  band 4.1-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q811B2

  48. NM_001404852.1 → NP_001391781.1  band 4.1-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q811B2

  49. NM_001404853.1 → NP_001391782.1  band 4.1-like protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    UniProtKB/TrEMBL
    Q811B2

  50. NM_001404854.1 → NP_001391783.1  band 4.1-like protein 2 isoform 21

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC153550, AC156274

  51. NM_001404855.1 → NP_001391784.1  band 4.1-like protein 2 isoform 21

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  52. NM_013511.4 → NP_038539.2  band 4.1-like protein 2 isoform 1

    See identical proteins and their annotated locations for NP_038539.2

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274
    Consensus CDS
    CCDS23754.1
    UniProtKB/Swiss-Prot
    G3X9B8, O70318
    UniProtKB/TrEMBL
    Q80UE3
    Related
    ENSMUSP00000090314.7, ENSMUST00000092645.7
    Conserved Domains (7) summary
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    cd14473
    Location:302 → 394
    FERM_B-lobe; FERM domain B-lobe
    pfam04382
    Location:613 → 656
    SAB; SAB domain
    pfam05902
    Location:876 → 978
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 542
    FA; FERM adjacent (FA)
    pfam09379
    Location:215 → 278
    FERM_N; FERM N-terminal domain

RNA

  1. NR_175869.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  2. NR_175870.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  3. NR_175871.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

  4. NR_175872.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC153547, AC156274

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    25235680..25399413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512506.2 → XP_006512569.1  band 4.1-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006512569.1

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:613 → 653
    SAB; SAB domain
    pfam05902
    Location:950 → 1052
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  2. XM_036155581.1 → XP_036011474.1  band 4.1-like protein 2 isoform X3

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:613 → 653
    SAB; SAB domain
    pfam05902
    Location:950 → 1019
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  3. XM_006512513.2 → XP_006512576.1  band 4.1-like protein 2 isoform X7

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:614 → 656
    SAB; SAB domain
    pfam05902
    Location:867 → 969
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 542
    FA; FERM adjacent (FA)

  4. XM_006512514.2 → XP_006512577.1  band 4.1-like protein 2 isoform X9

    UniProtKB/TrEMBL
    B6ZHC5
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:614 → 656
    SAB; SAB domain
    pfam05902
    Location:842 → 928
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 542
    FA; FERM adjacent (FA)

  5. XM_006512510.2 → XP_006512573.1  band 4.1-like protein 2 isoform X2

    UniProtKB/TrEMBL
    Q3UNQ6, Q80UE3
    Conserved Domains (6) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:594 → 635
    SAB; SAB domain
    pfam05902
    Location:929 → 1031
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 542
    FA; FERM adjacent (FA)

  6. XM_030244873.1 → XP_030100733.1  band 4.1-like protein 2 isoform X6

    UniProtKB/TrEMBL
    Q3UNQ6, Q80UE3
    Conserved Domains (6) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:594 → 635
    SAB; SAB domain
    pfam05902
    Location:873 → 975
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 542
    FA; FERM adjacent (FA)

  7. XM_036155582.1 → XP_036011475.1  band 4.1-like protein 2 isoform X8

    UniProtKB/TrEMBL
    Q3UNQ6, Q80UE3
    Conserved Domains (6) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:594 → 632
    SAB; SAB domain
    pfam05902
    Location:855 → 957
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  8. XM_006512512.2 → XP_006512575.1  band 4.1-like protein 2 isoform X5

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (5) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:880 → 982
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 542
    FA; FERM adjacent (FA)

  9. XM_036155587.1 → XP_036011480.1  band 4.1-like protein 2 isoform X16

    UniProtKB/TrEMBL
    B6ZHC5
    Conserved Domains (5) summary
    PTZ00121
    Location:9 → 203
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:716 → 802
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  10. XM_006512517.2 → XP_006512580.1  band 4.1-like protein 2 isoform X15

    UniProtKB/TrEMBL
    B6ZHC5
    Conserved Domains (5) summary
    PTZ00121
    Location:9 → 203
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:723 → 825
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  11. XM_036155579.1 → XP_036011472.1  band 4.1-like protein 2 isoform X1

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:613 → 653
    SAB; SAB domain
    pfam05902
    Location:950 → 1052
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  12. XM_036155580.1 → XP_036011473.1  band 4.1-like protein 2 isoform X1

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:613 → 653
    SAB; SAB domain
    pfam05902
    Location:950 → 1052
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  13. XM_006512507.5 → XP_006512570.1  band 4.1-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006512570.1

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:613 → 653
    SAB; SAB domain
    pfam05902
    Location:950 → 1052
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  14. XM_006512509.5 → XP_006512572.1  band 4.1-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006512572.1

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:613 → 653
    SAB; SAB domain
    pfam05902
    Location:950 → 1052
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  15. XM_036155578.1 → XP_036011471.1  band 4.1-like protein 2 isoform X1

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:613 → 653
    SAB; SAB domain
    pfam05902
    Location:950 → 1052
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  16. XM_036155577.1 → XP_036011470.1  band 4.1-like protein 2 isoform X1

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:613 → 653
    SAB; SAB domain
    pfam05902
    Location:950 → 1052
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

  17. XM_006512508.1 → XP_006512571.1  band 4.1-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006512571.1

    UniProtKB/TrEMBL
    Q80UE3
    Conserved Domains (7) summary
    PTZ00121
    Location:4 → 209
    PTZ00121; MAEBL; Provisional
    smart00295
    Location:213 → 402
    B41; Band 4.1 homologues
    PHA03247
    Location:642 → 745
    PHA03247; large tegument protein UL36; Provisional
    cd13184
    Location:397 → 490
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:613 → 653
    SAB; SAB domain
    pfam05902
    Location:950 → 1052
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:500 → 543
    FA; FERM adjacent (FA)

RNA

  1. XR_001779454.2 RNA Sequence

  2. XR_004936095.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O70318.2 GenPept UniProtKB/Swiss-Prot:O70318

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