Polr2D RNA polymerase II subunit D [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Polr2Dprovided by FlyBase
Official Full Name: RNA polymerase II subunit Dprovided by FlyBase
Primary source: FLYBASE:FBgn0263757
Locus tag: Dmel_CG43662
See related: AllianceGenome:FB:FBgn0263757
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG31237; CG33520; CG43662; CG7150; Dmel\CG43662; DmRpb4; DmRPB4; dRpb4; dRPB4; Rpb4; RPB4
Old locus tag: Dmel_CG33520
Summary: Predicted to enable translation initiation factor binding activity. Involved in transcription by RNA polymerase II. Located in polytene chromosome interband and polytene chromosome puff. Part of RNA polymerase II, core complex. Is expressed in embryonic brain; embryonic/larval midgut; larval ventral nerve cord; and organism. Orthologous to human POLR2D (RNA polymerase II subunit D). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (18252843..18255487, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (14078565..14081209, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables translation initiation factor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription initiation	IEA Inferred from Electronic Annotation more info
involved_in transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in transcription initiation at RNA polymerase II promoter	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of RNA polymerase II, core complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase II, core complex	IDA Inferred from Direct Assay more info	PubMed
part_of RNA polymerase II, core complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of RNA polymerase complex	IEA Inferred from Electronic Annotation more info
located_in polytene chromosome	IDA Inferred from Direct Assay more info	PubMed
located_in polytene chromosome interband	IDA Inferred from Direct Assay more info	PubMed
located_in polytene chromosome puff	IDA Inferred from Direct Assay more info	PubMed

Names: CG43662-PF; Polr2D-PF; RNA polymerase II; RNA polymerase II subunit Rpb4; Rpb4

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The following sections contain reference sequences that belong to a specific genome build. Explain