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CG44008 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 14462750, updated on 4-Jan-2025

Summary

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Official Symbol
CG44008provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0264750
Locus tag
Dmel_CG44008
See related
AllianceGenome:FB:FBgn0264750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG31758; CG42325; Dmel\CG44008
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Involved in sexual reproduction. Located in extracellular space. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG44008 in Genome Data Viewer
Location:
33A3-33A3; 2-45 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11841502..11842445, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11841502..11842445, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phosphodiesterase 1c Neighboring gene antisense RNA:CR43936 Neighboring gene Seminal fluid protein 33A3 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Maltase B1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila soluble guanylyl cyclase mutants exhibit increased foraging locomotion: behavioral and genomic investigations. Riedl CA, et al. Behav Genet, 2005 May. PMID 15864439
  2. Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Mangleburg CG, et al. Mol Neurodegener, 2020 Sep 29. PMID 32993812, Free PMC Article
  3. Drosophila microbiota modulates host metabolic gene expression via IMD/NF-κB signaling. Erkosar B, et al. PLoS One, 2014. PMID 24733183, Free PMC Article
  4. Endogenously imprinted genes in Drosophila melanogaster. McEachern LA, et al. Mol Genet Genomics, 2014 Aug. PMID 24658702
  5. Proteomics reveals novel Drosophila seminal fluid proteins transferred at mating. Findlay GD, et al. PLoS Biol, 2008 Jul 29. PMID 18666829, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity ISM
Inferred from Sequence Model
more info
  
Process Evidence Code Pubs
involved_in sexual reproduction HEP PubMed 
Component Evidence Code Pubs
located_in extracellular space HDA PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG44008-PA
CG44008-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    11841502..11842445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273469.1 → NP_001260398.1  uncharacterized protein Dmel_CG44008, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260398.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBA3
    Conserved Domains (1) summary
    cd00104
    Location:36 → 79
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...

  2. NM_001298922.1 → NP_001285851.1  uncharacterized protein Dmel_CG44008, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285851.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PBA3
    Conserved Domains (1) summary
    cd00104
    Location:36 → 79
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PBA3 M9PBA3

Gene LinkOut

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Molecular Biology Databases
Research Materials