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ACA1_018960 papain family cysteine protease subfamily protein [ Acanthamoeba castellanii str. Neff ]

Gene ID: 14926814, updated on 17-May-2024

Summary

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Gene symbol
ACA1_018960
Gene description
papain family cysteine protease subfamily protein
Locus tag
ACA1_018960
See related
AmoebaDB:ACA1_018960; VEuPathDB:ACA1_018960
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Acanthamoeba castellanii str. Neff (strain: Neff, culture-collection: ATCC:30010)
Lineage
Eukaryota; Amoebozoa; Discosea; Longamoebia; Centramoebida; Acanthamoebidae; Acanthamoeba
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Genomic context

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See ACA1_018960 in Genome Data Viewer
Location:
chromosome: Unknown
Exon count:
7

NW_004457733.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene lipoprotein, putative Neighboring gene uncharacterized protein Neighboring gene GTP cyclohydrolase II, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004457733.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling. Clarke M, et al. Genome Biol, 2013 Feb 1. PMID 23375108, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
papain family cysteine protease subfamily protein
XP_004358308.1
  • encoded by transcript ACA1_018960A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NW_004457733.1 Reference assembly

    Range
    34120..35989 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004358251.1 → XP_004358308.1  papain family cysteine protease subfamily protein [Acanthamoeba castellanii str. Neff]

    See identical proteins and their annotated locations for XP_004358308.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    L8HJH5
    Conserved Domains (2) summary
    smart00848
    Location:41 → 97
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    cd02248
    Location:134 → 348
    Peptidase_C1A; Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences, ...
Nucleotide Protein
Heading Accession and Version

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