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hemC hydroxymethylbilane synthase [ Sulfolobus islandicus LAL14/1 ]

Gene ID: 15298335, updated on 29-Sep-2023

Summary

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Gene symbol
hemC
Gene description
hydroxymethylbilane synthase
Locus tag
SIL_RS09090
Gene type
protein coding
Organism
Sulfolobus islandicus LAL14/1 (strain: LAL14/1)
Lineage
Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus
Old locus tag
SiL_1806
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Genomic context

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Sequence:
NC_021058.1 (1661400..1662281, complement)

NC_021058.1Genomic Context describing neighboring genes Neighboring gene (2Fe-2S)-binding protein Neighboring gene alkaline phosphatase family protein Neighboring gene hypothetical protein Neighboring gene uroporphyrinogen-III synthase Neighboring gene glutamate-1-semialdehyde 2,1-aminomutase Neighboring gene porphobilinogen synthase Neighboring gene glutamyl-tRNA reductase Neighboring gene bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_021058.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The three-dimensional structure of Escherichia coli porphobilinogen deaminase at 1.76-A resolution. Louie GV, et al. Proteins, 1996 May. PMID 8727319
  2. Purification, characterization, crystallisation and X-ray analysis of selenomethionine-labelled hydroxymethylbilane synthase from Escherichia coli. Hädener A, et al. Eur J Biochem, 1993 Feb 1. PMID 8436121
  3. Cloning and sequencing of some genes responsible for porphyrin biosynthesis from the anaerobic bacterium Clostridium josui. Fujino E, et al. J Bacteriol, 1995 Sep. PMID 7665501, Free PMC Article
  4. Genomics and genetics of Sulfolobus islandicus LAL14/1, a model hyperthermophilic archaeon. Jaubert C, et al. Open Biol, 2013 Apr 17. PMID 23594878, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
hydroxymethylbilane synthase
WP_014512866.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_021058.1 Reference assembly

    Range
    1661400..1662281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_014512866.1 hydroxymethylbilane synthase [Sulfolobus islandicus]

    See identical proteins and their annotated locations for WP_014512866.1

    UniProtKB/TrEMBL
    F0NI03, F0NQ41, M9UAV4
    Conserved Domains (2) summary
    COG0181
    Location:1 → 293
    HemC; Porphobilinogen deaminase [Coenzyme transport and metabolism]
    cd13644
    Location:2 → 268
    PBP2_HemC_archaea; Archaeal HemC of hydroxymethylbilane synthase family; the type 2 periplasmic binding protein fold