U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Klra1 killer cell lectin-like receptor, subfamily A, member 1 [ Mus musculus (house mouse) ]

Gene ID: 16627, updated on 27-Nov-2024

Summary

Official Symbol
Klra1provided by MGI
Official Full Name
killer cell lectin-like receptor, subfamily A, member 1provided by MGI
Primary source
MGI:MGI:101907
See related
Ensembl:ENSMUSG00000079853 AllianceGenome:MGI:101907
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A1; Ly49a; Ly49v; Klra22; Ly49o<129>; CH29-493D4.3
Summary
Enables signaling receptor activity. Predicted to be involved in regulation of signal transduction. Located in external side of plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Klra1 in Genome Data Viewer
Location:
6 F3; 6 63.44 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (130340881..130363837, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (130363918..130386874, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 24072 Neighboring gene killer cell lectin-like receptor, subfamily A, member 3 Neighboring gene predicted gene 6584 Neighboring gene predicted gene 6590

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables signaling receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
T-cell surface glycoprotein YE1/48
Names
class I MHC receptor KLRA22
ly-49a
lymphocyte antigen 49a
natural killer cell receptor Ly49A
novel killer cell lectin-like receptor subfamily A protein
t lymphocyte antigen A1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016659.3NP_057868.2  T-cell surface glycoprotein YE1/48

    See identical proteins and their annotated locations for NP_057868.2

    Status: VALIDATED

    Source sequence(s)
    AC087336, AK080158
    Consensus CDS
    CCDS20602.1
    UniProtKB/TrEMBL
    Q8BNV4, Q8MHR8, Q925C6
    Related
    ENSMUSP00000032288.5, ENSMUST00000032288.6
    Conserved Domains (2) summary
    cd03593
    Location:142255
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
    pfam08391
    Location:40153
    Ly49; Ly49-like protein, N-terminal region

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    130340881..130363837 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)