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Adgrl2 adhesion G protein-coupled receptor L2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 171447, updated on 27-Nov-2024

Summary

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Official Symbol
Adgrl2provided by RGD
Official Full Name
adhesion G protein-coupled receptor L2provided by RGD
Primary source
RGD:620835
See related
EnsemblRapid:ENSRNOG00000065347 AllianceGenome:RGD:620835
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Cirl2; Cl2ac; Lphn2; Cirl-2
Summary
Enables PDZ domain binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and synapse organization. Predicted to act upstream of or within positive regulation of synapse assembly and response to bacterium. Predicted to be located in membrane. Predicted to be active in glutamatergic synapse and postsynaptic membrane. Orthologous to human ADGRL2 (adhesion G protein-coupled receptor L2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 155.2), Liver (RPKM 125.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Adgrl2 in Genome Data Viewer
Location:
2q45
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (240356176..240987246, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (237696055..238327141, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (258792838..258997145, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC134486003 Neighboring gene uncharacterized LOC120101103 Neighboring gene uncharacterized LOC102547720 Neighboring gene uncharacterized LOC134486004 Neighboring gene uncharacterized LOC102547649 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC120101101 Neighboring gene uncharacterized LOC134486005 Neighboring gene uncharacterized LOC102547779

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Postsynaptic adhesion GPCR latrophilin-2 mediates target recognition in entorhinal-hippocampal synapse assembly. Anderson GR, et al. J Cell Biol, 2017 Nov 6. PMID 28972101, Free PMC Article
  2. A novel ubiquitously expressed alpha-latrotoxin receptor is a member of the CIRL family of G-protein-coupled receptors. Ichtchenko K, et al. J Biol Chem, 1999 Feb 26. PMID 10026162
  3. A de novo variant in ADGRL2 suggests a novel mechanism underlying the previously undescribed association of extreme microcephaly with severely reduced sulcation and rhombencephalosynapsis. Vezain M, et al. Acta Neuropathol Commun, 2018 Oct 19. PMID 30340542, Free PMC Article
  4. alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis. Sugita S, et al. J Biol Chem, 1998 Dec 4. PMID 9830014
  5. The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins. Kreienkamp HJ, et al. J Biol Chem, 2000 Oct 20. PMID 10964907

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables G protein-coupled receptor activity TAS
Traceable Author Statement
more info
 PubMed 
enables PDZ domain binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of synapse assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within response to bacterium ISO
Inferred from Sequence Orthology
more info
  
involved_in synapse organization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in postsynaptic membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
adhesion G protein-coupled receptor L2
Names
calcium-independent alpha-latrotoxin receptor 2
calcium-independent alpha-latrotoxin receptor homolog 2
latrophilin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190475.2 → NP_001177404.2  adhesion G protein-coupled receptor L2 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001177404.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (2) is shorter, compared to isoform 1.
    Source sequence(s)
    AA899882, AF063102, AF081153, CB579130, CO556290, FM039554, FM068641, FM099106
    UniProtKB/TrEMBL
    A0A8I6A5I7, A6HWH0, D3ZBE9
    Related
    ENSRNOP00000042136.6, ENSRNOT00000045905.7
    Conserved Domains (8) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1119 → 1478
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:850 → 875
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain
    cl28897
    Location:848 → 1120
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. NM_001302208.1 → NP_001289137.1  adhesion G protein-coupled receptor L2 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001289137.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an in-frame exon and has an alternate splice site in the 3' coding region, compared to variant 1. The resulting isoform (3) is shorter and lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AA899882, AF063102, AF081151, CB579130, CO556290, FM039554, FM068641, FM099106
    UniProtKB/TrEMBL
    A6HWG7
    Related
    ENSRNOP00000098507.2, ENSRNOT00000120902.2
    Conserved Domains (8) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1119 → 1467
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:850 → 875
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain
    cl28897
    Location:848 → 1120
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. NM_001302209.1 → NP_001289138.1  adhesion G protein-coupled receptor L2 isoform 4 precursor

    See identical proteins and their annotated locations for NP_001289138.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks two consecutive exons in the 3' coding region, but maintains the reading frame, compared to variant 1. The resulting isoform (4) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AA899882, AF063102, AF081150, CB579130, CO556290, FM039554, FM068641, FM099106
    UniProtKB/TrEMBL
    A6HWG5
    Related
    ENSRNOP00000098504.2, ENSRNOT00000120899.2
    Conserved Domains (8) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1463
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:850 → 875
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain
    cl28897
    Location:848 → 1105
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  4. NM_001302210.1 → NP_001289139.1  adhesion G protein-coupled receptor L2 isoform 5 precursor

    See identical proteins and their annotated locations for NP_001289139.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks two consecutive exons and has an alternate splice site in the 3' coding region, but maintains the reading frame, compared to variant 1. The resulting isoform (5) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AA899882, AF063102, AF081148, CB579130, CO556290, FM039554, FM068641, FM099106
    UniProtKB/TrEMBL
    A6HWG0
    Conserved Domains (8) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1452
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:850 → 875
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain
    cl28897
    Location:848 → 1105
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  5. NM_001302211.1 → NP_001289140.1  adhesion G protein-coupled receptor L2 isoform 6 precursor

    See identical proteins and their annotated locations for NP_001289140.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks two in-frame exons in the 3' coding region, but maintains the reading frame, compared to variant 1. The resulting isoform (6) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AA899882, AF063102, AF081152, CB579130, CO556290, FM039554, FM068641, FM099106
    UniProtKB/TrEMBL
    A0A8I5ZZY9, A6HWG9
    Conserved Domains (8) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1119 → 1435
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:850 → 875
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain
    cl28897
    Location:848 → 1120
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  6. NM_001302212.1 → NP_001289141.1  adhesion G protein-coupled receptor L2 isoform 7 precursor

    See identical proteins and their annotated locations for NP_001289141.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks three exons in the 3' coding region, but maintains the reading frame, compared to variant 1. The resulting isoform (7) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AA899882, AF063102, AF081149, CB579130, CO556290, FM039554, FM068641, FM099106
    UniProtKB/TrEMBL
    A6HWG3
    Conserved Domains (8) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1104 → 1420
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:850 → 875
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain
    cl28897
    Location:848 → 1105
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  7. NM_134408.3 → NP_599235.3  adhesion G protein-coupled receptor L2 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AA899882, AF063102, AF081148, AF081151, CB579130, CO556290, FM039554, FM068641, FM099106
    UniProtKB/Swiss-Prot
    O88918, O88919, O88920, O88921, O88922, O88923, Q9Z174
    UniProtKB/TrEMBL
    F1M7T0
    Conserved Domains (8) summary
    smart00303
    Location:788 → 840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469 → 533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1128 → 1487
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542 → 764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:850 → 875
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:142 → 398
    OLF; Olfactomedin-like domain
    cl28897
    Location:848 → 1129
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    240356176..240987246 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063281223.1 → XP_063137293.1  adhesion G protein-coupled receptor L2 isoform X1

  2. XM_063281268.1 → XP_063137338.1  adhesion G protein-coupled receptor L2 isoform X40

  3. XM_063281246.1 → XP_063137316.1  adhesion G protein-coupled receptor L2 isoform X20

    UniProtKB/TrEMBL
    A0A8I5ZUN4

  4. XM_063281234.1 → XP_063137304.1  adhesion G protein-coupled receptor L2 isoform X10

  5. XM_063281264.1 → XP_063137334.1  adhesion G protein-coupled receptor L2 isoform X37

  6. XM_063281231.1 → XP_063137301.1  adhesion G protein-coupled receptor L2 isoform X7

  7. XM_063281225.1 → XP_063137295.1  adhesion G protein-coupled receptor L2 isoform X1

  8. XM_063281245.1 → XP_063137315.1  adhesion G protein-coupled receptor L2 isoform X20

    UniProtKB/TrEMBL
    A0A8I5ZUN4

  9. XM_063281266.1 → XP_063137336.1  adhesion G protein-coupled receptor L2 isoform X38

  10. XM_063281239.1 → XP_063137309.1  adhesion G protein-coupled receptor L2 isoform X16

  11. XM_063281224.1 → XP_063137294.1  adhesion G protein-coupled receptor L2 isoform X1

  12. XM_063281254.1 → XP_063137324.1  adhesion G protein-coupled receptor L2 isoform X28

  13. XM_063281250.1 → XP_063137320.1  adhesion G protein-coupled receptor L2 isoform X24

  14. XM_063281252.1 → XP_063137322.1  adhesion G protein-coupled receptor L2 isoform X26

  15. XM_063281247.1 → XP_063137317.1  adhesion G protein-coupled receptor L2 isoform X21

  16. XM_063281253.1 → XP_063137323.1  adhesion G protein-coupled receptor L2 isoform X27

  17. XM_063281248.1 → XP_063137318.1  adhesion G protein-coupled receptor L2 isoform X22

  18. XM_063281251.1 → XP_063137321.1  adhesion G protein-coupled receptor L2 isoform X25

  19. XM_063281240.1 → XP_063137310.1  adhesion G protein-coupled receptor L2 isoform X17

  20. XM_063281238.1 → XP_063137308.1  adhesion G protein-coupled receptor L2 isoform X15

  21. XM_063281249.1 → XP_063137319.1  adhesion G protein-coupled receptor L2 isoform X23

  22. XM_039101650.2 → XP_038957578.1  adhesion G protein-coupled receptor L2 isoform X20

    UniProtKB/TrEMBL
    A0A8I5ZUN4, A6HWG3
    Conserved Domains (8) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1403
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833 → 858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain
    cl28897
    Location:831 → 1088
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  23. XM_063281265.1 → XP_063137335.1  adhesion G protein-coupled receptor L2 isoform X38

  24. XM_039101639.2 → XP_038957567.1  adhesion G protein-coupled receptor L2 isoform X10

    UniProtKB/TrEMBL
    A6HWG5
    Related
    ENSRNOP00000083029.2, ENSRNOT00000109156.2
    Conserved Domains (8) summary
    smart00303
    Location:771 → 823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1087 → 1446
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833 → 858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain
    cl28897
    Location:831 → 1088
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  25. XM_063281243.1 → XP_063137313.1  adhesion G protein-coupled receptor L2 isoform X18

  26. XM_063281237.1 → XP_063137307.1  adhesion G protein-coupled receptor L2 isoform X14

  27. XM_063281229.1 → XP_063137299.1  adhesion G protein-coupled receptor L2 isoform X6

  28. XM_063281230.1 → XP_063137300.1  adhesion G protein-coupled receptor L2 isoform X8

  29. XM_063281227.1 → XP_063137297.1  adhesion G protein-coupled receptor L2 isoform X4

  30. XM_063281244.1 → XP_063137314.1  adhesion G protein-coupled receptor L2 isoform X19

  31. XM_063281232.1 → XP_063137302.1  adhesion G protein-coupled receptor L2 isoform X9

  32. XM_039101645.2 → XP_038957573.1  adhesion G protein-coupled receptor L2 isoform X16

    UniProtKB/TrEMBL
    A6HWG3
    Conserved Domains (8) summary
    smart00303
    Location:784 → 836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1100 → 1416
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 760
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:846 → 871
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain
    cl28897
    Location:844 → 1101
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  33. XM_063281263.1 → XP_063137333.1  adhesion G protein-coupled receptor L2 isoform X37

  34. XM_039101637.2 → XP_038957565.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A6HWG5
    Related
    ENSRNOP00000098502.2, ENSRNOT00000120897.2
    Conserved Domains (8) summary
    smart00303
    Location:784 → 836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1100 → 1459
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 760
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:846 → 871
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain
    cl28897
    Location:844 → 1101
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  35. XM_063281228.1 → XP_063137298.1  adhesion G protein-coupled receptor L2 isoform X5

  36. XM_063281235.1 → XP_063137305.1  adhesion G protein-coupled receptor L2 isoform X12

  37. XM_039101632.2 → XP_038957560.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/TrEMBL
    A6HWH0, D3ZBE9
    Related
    ENSRNOP00000089949.3, ENSRNOT00000116263.3
    Conserved Domains (8) summary
    smart00303
    Location:784 → 836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465 → 529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49 → 129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:1115 → 1474
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538 → 760
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:846 → 871
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138 → 394
    OLF; Olfactomedin-like domain
    cl28897
    Location:844 → 1116
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  38. XM_063281236.1 → XP_063137306.1  adhesion G protein-coupled receptor L2 isoform X13

  39. XM_063281261.1 → XP_063137331.1  adhesion G protein-coupled receptor L2 isoform X35

  40. XM_063281226.1 → XP_063137296.1  adhesion G protein-coupled receptor L2 isoform X3

  41. XM_063281233.1 → XP_063137303.1  adhesion G protein-coupled receptor L2 isoform X11

    Related
    ENSRNOP00000095749.2, ENSRNOT00000095993.2

  42. XM_063281259.1 → XP_063137329.1  adhesion G protein-coupled receptor L2 isoform X33

  43. XM_063281222.1 → XP_063137292.1  adhesion G protein-coupled receptor L2 isoform X1

  44. XM_063281255.1 → XP_063137325.1  adhesion G protein-coupled receptor L2 isoform X29

  45. XM_063281257.1 → XP_063137327.1  adhesion G protein-coupled receptor L2 isoform X31

  46. XM_063281256.1 → XP_063137326.1  adhesion G protein-coupled receptor L2 isoform X30

  47. XM_063281258.1 → XP_063137328.1  adhesion G protein-coupled receptor L2 isoform X32

  48. XM_063281262.1 → XP_063137332.1  adhesion G protein-coupled receptor L2 isoform X36

  49. XM_063281260.1 → XP_063137330.1  adhesion G protein-coupled receptor L2 isoform X34

  50. XM_063281267.1 → XP_063137337.1  adhesion G protein-coupled receptor L2 isoform X39

    Related
    ENSRNOP00000098509.2, ENSRNOT00000120904.2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O88923.2 GenPept UniProtKB/Swiss-Prot:O88923

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