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Y74C10AL.2 Transmembrane protein 50A [ Caenorhabditis elegans ]

Gene ID: 171806, updated on 2-Nov-2024

Summary

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Official Symbol
Y74C10AL.2
Official Full Name
Transmembrane protein 50A
Primary source
WormBase:WBGene00022280
Locus tag
CELE_Y74C10AL.2
See related
AllianceGenome:WB:WBGene00022280
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway. Predicted to be located in membrane. Orthologous to human TMEM50A (transmembrane protein 50A) and TMEM50B (transmembrane protein 50B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y74C10AL.2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003279.8 (2468793..2471935, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Innexin-19 Neighboring gene ABC transmembrane type-1 domain-containing protein;Iron-sulfur clusters transporter ABCB7, mitochondrial Neighboring gene Conserved secreted protein Neighboring gene Eukaryotic translation initiation factor 3 subunit I;Serine-threonine kinase receptor-associated protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in late endosome to vacuole transport via multivesicular body sorting pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Transmembrane protein 50A
NP_490985.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    2468793..2471935 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058584.9 → NP_490985.1  Transmembrane protein 50A [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_490985.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N2X7
    Conserved Domains (1) summary
    pfam05255
    Location:5 → 156
    UPF0220; uncharacterized protein family (UPF0220)
Nucleotide Protein
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