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Y71F9AL.10 RING-type E3 ubiquitin transferase [ Caenorhabditis elegans ]

Gene ID: 171852, updated on 2-Nov-2024

Summary

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Official Symbol
Y71F9AL.10
Official Full Name
RING-type E3 ubiquitin transferase
Primary source
WormBase:WBGene00022115
Locus tag
CELE_Y71F9AL.10
See related
AllianceGenome:WB:WBGene00022115
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein K48-linked ubiquitination. Predicted to be located in lysosome. Predicted to be active in cytoplasm; intracellular membrane-bounded organelle; and membrane. Orthologous to human ZNRF1 (zinc and ring finger 1) and ZNRF2 (zinc and ring finger 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y71F9AL.10 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003279.8 (2866506..2870172)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Plasma membrane proteolipid 3 Neighboring gene ncRNA Neighboring gene DUF3306 domain-containing protein;Increased recombination centers protein 6;Pre-rRNA-processing protein TSR2 homolog;UAE_UbL domain-containing protein Neighboring gene Large ribosomal subunit protein uL1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein K48-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RING-type E3 ubiquitin transferase
NP_001360588.1
  • Confirmed by transcript evidence
NP_001360589.1
  • Confirmed by transcript evidence
NP_001360590.1
  • Confirmed by transcript evidence
NP_001360591.1
  • Confirmed by transcript evidence
NP_491059.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    2866506..2870172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373751.2 → NP_001360588.1  RING-type E3 ubiquitin transferase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IMW1
    Conserved Domains (1) summary
    cd16489
    Location:123 → 165
    mRING-CH-C4HC2H_ZNRF; Modified RING-CH finger, H2 subclass (C4HC2H-type), found in the ZNRF family

  2. NM_001373752.1 → NP_001360589.1  RING-type E3 ubiquitin transferase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IMP7
    Conserved Domains (1) summary
    cd16489
    Location:142 → 184
    mRING-CH-C4HC2H_ZNRF; Modified RING-CH finger, H2 subclass (C4HC2H-type), found in the ZNRF family

  3. NM_001373753.3 → NP_001360590.1  RING-type E3 ubiquitin transferase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V6Z7Z0
    Conserved Domains (1) summary
    cd16489
    Location:121 → 163
    mRING-CH-C4HC2H_ZNRF; Modified RING-CH finger, H2 subclass (C4HC2H-type), found in the ZNRF family

  4. NM_058658.9 → NP_491059.2  RING-type E3 ubiquitin transferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491059.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N4I6
    Conserved Domains (1) summary
    cd16489
    Location:144 → 186
    mRING-CH-C4HC2H_ZNRF; Modified RING-CH finger, H2 subclass (C4HC2H-type), found in the ZNRF family

  5. NM_001373757.2 → NP_001360591.1  RING-type E3 ubiquitin transferase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4V0IJT2
    Conserved Domains (1) summary
    cd16489
    Location:107 → 149
    mRING-CH-C4HC2H_ZNRF; Modified RING-CH finger, H2 subclass (C4HC2H-type), found in the ZNRF family
Nucleotide Protein
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