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clec-53 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 171967, updated on 4-Jan-2025

Summary

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Official Symbol
clec-53
Official Full Name
C-type lectin domain-containing protein
Primary source
WormBase:WBGene00020191
Locus tag
CELE_T03F1.10
See related
AllianceGenome:WB:WBGene00020191
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable signaling receptor activity. Is expressed in intestine. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human REG1A (regenerating family member 1 alpha). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See clec-53 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (3871474..3873402, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Ubiquinone biosynthesis protein coq-4, mitochondrial Neighboring gene ncRNA Neighboring gene Ubiquitin-like modifier-activating enzyme 5 Neighboring gene Protein SYS1 homolog Neighboring gene Pre-mRNA-splicing factor SYF1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Roles for the RNA polymerase III regulator MAFR-1 in regulating sperm quality in Caenorhabditis elegans. Hammerquist AM, et al. Sci Rep, 2020 Nov 9. PMID 33168938, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
C-type lectin domain-containing protein
NP_491247.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3871474..3873402 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058846.6 → NP_491247.2  C-type lectin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491247.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91429
    Conserved Domains (2) summary
    cd00037
    Location:32 → 147
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    smart00034
    Location:166 → 303
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
Nucleotide Protein
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