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kel-20 BTB domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172012, updated on 2-Nov-2024

Summary

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Official Symbol
kel-20
Official Full Name
BTB domain-containing protein
Primary source
WormBase:WBGene00020030
Locus tag
CELE_R12E2.1
See related
AllianceGenome:WB:WBGene00020030
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in intestine and nervous system. Orthologous to human KLHL20 (kelch like family member 20). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See kel-20 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003279.8 (4182221..4184992)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene MIR domain-containing protein Neighboring gene SUN domain-containing protein Neighboring gene Piwi domain-containing protein Neighboring gene C-CAP/cofactor C-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Loss of the insulator protein CTCF during nematode evolution. Heger P, et al. BMC Mol Biol, 2009 Aug 27. PMID 19712444, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ubiquitin-like ligase-substrate adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Cul3-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BTB domain-containing protein
NP_491322.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    4182221..4184992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058921.7 → NP_491322.2  BTB domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491322.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O61795
    Conserved Domains (2) summary
    PHA03098
    Location:56 → 572
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:345 → 389
    Kelch; KELCH repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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