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ctnb-1 Beta-catenin-like protein 1 N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172214, updated on 2-Nov-2024

Summary

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Official Symbol
ctnb-1
Official Full Name
Beta-catenin-like protein 1 N-terminal domain-containing protein
Primary source
WormBase:WBGene00019711
Locus tag
CELE_M01E11.2
See related
AllianceGenome:WB:WBGene00019711
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is expressed in head muscle; intestine; nerve ring; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in colorectal cancer; morbid obesity; and primary immunodeficiency disease. Orthologous to human CTNNBL1 (catenin beta like 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ctnb-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (5579666..5581993)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RecQ-mediated genome instability protein 1 homolog Neighboring gene Kinesin motor domain-containing protein Neighboring gene Protein-S-isoprenylcysteine O-methyltransferase Neighboring gene Tensin homolog Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development. Arur S, et al. Proc Natl Acad Sci U S A, 2009 Mar 24. PMID 19264959, Free PMC Article
  2. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  3. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Beta-catenin-like protein 1 N-terminal domain-containing protein
NP_491634.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5579666..5581993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059233.6 → NP_491634.1  Beta-catenin-like protein 1 N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491634.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91401
    Conserved Domains (1) summary
    pfam08216
    Location:43 → 144
    CTNNBL; Catenin-beta-like, Arm-motif containing nuclear
Nucleotide Protein
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