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F55F8.2 ATP-dependent RNA helicase [ Caenorhabditis elegans ]

Gene ID: 172223, updated on 4-Jan-2025

Summary

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Official Symbol
F55F8.2
Official Full Name
ATP-dependent RNA helicase
Primary source
WormBase:WBGene00018890
Locus tag
CELE_F55F8.2
See related
AllianceGenome:WB:WBGene00018890
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be active in nucleolus. Orthologous to human DDX24 (DEAD-box helicase 24). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See F55F8.2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
8
Sequence:
Chromosome: I; NC_003279.8 (5646369..5649656, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase Neighboring gene Protein-tyrosine phosphatase catalytic domain-containing protein Neighboring gene Col_cuticle_N domain-containing protein Neighboring gene Periodic tryptophan protein 2 homolog Neighboring gene CBF1-interacting co-repressor CIR N-terminal domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. Akay A, et al. Dev Cell, 2017 Aug 7. PMID 28787591, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ATP-dependent RNA helicase
NP_491652.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5646369..5649656 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059251.5 → NP_491652.1  ATP-dependent RNA helicase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491652.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    P91340
    Conserved Domains (4) summary
    COG0513
    Location:160 → 618
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    pfam00271
    Location:427 → 534
    Helicase_C; Helicase conserved C-terminal domain
    pfam11861
    Location:40 → 106
    DUF3381; Domain of unknown function (DUF3381)
    cl21455
    Location:162 → 362
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RNA

  1. NR_144559.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

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