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pdpr-1 DAO domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 172922, updated on 2-Nov-2024

Summary

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Official Symbol
pdpr-1
Official Full Name
DAO domain-containing protein
Primary source
WormBase:WBGene00013718
Locus tag
CELE_Y106G6H.5
See related
AllianceGenome:WB:WBGene00013718
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in mitochondrial matrix. Orthologous to human PDPR (pyruvate dehydrogenase phosphatase regulatory subunit). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pdpr-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
11
Sequence:
Chromosome: I; NC_003279.8 (10438075..10443563, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Large ribosomal subunit protein eL30 Neighboring gene MADF domain-containing protein Neighboring gene MalT-like TPR region domain-containing protein;TPR_REGION domain-containing protein Neighboring gene Exocyst complex component 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DAO domain-containing protein
NP_492730.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    10438075..10443563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060329.5 → NP_492730.2  DAO domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492730.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U300
    Conserved Domains (6) summary
    COG0404
    Location:439 → 833
    GcvT; Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]
    pfam01266
    Location:23 → 387
    DAO; FAD dependent oxidoreductase
    pfam01571
    Location:449 → 724
    GCV_T; Aminomethyltransferase folate-binding domain
    pfam08669
    Location:733 → 833
    GCV_T_C; Glycine cleavage T-protein C-terminal barrel domain
    pfam13450
    Location:28 → 54
    NAD_binding_8; NAD(P)-binding Rossmann-like domain
    pfam16350
    Location:394 → 445
    FAO_M; FAD dependent oxidoreductase central domain
Nucleotide Protein
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