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fdps-1 Farnesyl pyrophosphate synthase [ Caenorhabditis elegans ]

Gene ID: 173075, updated on 2-Nov-2024

Summary

Official Symbol
fdps-1
Official Full Name
Farnesyl pyrophosphate synthase
Primary source
WormBase:WBGene00011058
Locus tag
CELE_R06C1.2
See related
AllianceGenome:WB:WBGene00011058
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable dimethylallyltranstransferase activity and geranyltranstransferase activity. Predicted to be involved in farnesyl diphosphate biosynthetic process. Predicted to be active in cytoplasm. Is expressed in germ line. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human FDPS (farnesyl diphosphate synthase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See fdps-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (11917806..11923915, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene NEDD8-conjugating enzyme ubc-12 Neighboring gene Protein mago nashi homolog Neighboring gene Histone deacetylase Neighboring gene WH2 domain-containing protein;Wiskott-Aldrich syndrome protein family member Neighboring gene RRM domain-containing protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables dimethylallyltranstransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables geranyltranstransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity, transferring alkyl or aryl (other than methyl) groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in farnesyl diphosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in isoprenoid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in pheromone biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Farnesyl pyrophosphate synthase
NP_493027.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    11917806..11923915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060626.7NP_493027.1  Farnesyl pyrophosphate synthase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493027.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62336
    Conserved Domains (1) summary
    cd00685
    Location:44268
    Trans_IPPS_HT; Trans-Isoprenyl Diphosphate Synthases, head-to-tail