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amx-2 monoamine oxidase [ Caenorhabditis elegans ]

Gene ID: 173146, updated on 4-Jan-2025

Summary

Official Symbol
amx-2
Official Full Name
monoamine oxidase
Primary source
WormBase:WBGene00000138
Locus tag
CELE_B0019.1
See related
AllianceGenome:WB:WBGene00000138
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable oxidoreductase activity. Predicted to be located in mitochondrial outer membrane. Is expressed in several structures, including HSN; anus; pharyngeal muscle cell; rectal epithelium; and vulva. Human ortholog(s) of this gene implicated in Brunner Syndrome; alcohol use disorder; autism spectrum disorder; neurodegenerative disease (multiple); and panic disorder. Orthologous to several human genes including MAOA (monoamine oxidase A). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See amx-2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
15
Sequence:
Chromosome: I; NC_003279.8 (12759587..12764960, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene BTB domain-containing protein Neighboring gene SPK domain-containing protein Neighboring gene ncRNA Neighboring gene pseudo

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
monoamine oxidase
NP_001369790.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    12759587..12764960 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383739.2NP_001369790.1  monoamine oxidase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XXU5
    Conserved Domains (1) summary
    pfam01593
    Location:55472
    Amino_oxidase; Flavin containing amine oxidoreductase