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oxa-1 Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173207, updated on 2-Nov-2024

Summary

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Official Symbol
oxa-1
Official Full Name
Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein
Primary source
WormBase:WBGene00007215
Locus tag
CELE_C01A2.3
See related
AllianceGenome:WB:WBGene00007215
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable membrane insertase activity. Predicted to be involved in protein insertion into mitochondrial inner membrane from matrix. Located in mitochondrion. Is expressed in body wall musculature and pharyngeal muscle cell. Orthologous to human OXA1L (OXA1L mitochondrial inner membrane protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See oxa-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (13387819..13391205)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene WWE domain-containing protein Neighboring gene Replication termination factor 2 Neighboring gene Charged multivesicular body protein 2b Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The SFT-1 and OXA-1 respiratory chain complex assembly factors influence lifespan by distinct mechanisms in C. elegans. Maxwell S, et al. Longev Healthspan, 2013 May 8. PMID 24472117, Free PMC Article
  2. Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi. Simmer F, et al. Curr Biol, 2002 Aug 6. PMID 12176360
  3. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
  4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables membrane insertase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables membrane insertase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein insertion into mitochondrial inner membrane from matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein
NP_493356.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    13387819..13391205
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060955.8 → NP_493356.2  Membrane insertase YidC/Oxa/ALB C-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493356.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O02207
    Conserved Domains (1) summary
    cl00489
    Location:106 → 296
    60KD_IMP; 60Kd inner membrane protein
Nucleotide Protein
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