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slc-30A5 Proton-coupled zinc antiporter SLC30A5 [ Caenorhabditis elegans ]

Gene ID: 173299, updated on 2-Nov-2024

Summary

Official Symbol
slc-30A5
Official Full Name
Proton-coupled zinc antiporter SLC30A5
Primary source
WormBase:WBGene00013668
Locus tag
CELE_Y105E8A.3
See related
AllianceGenome:WB:WBGene00013668
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion import into Golgi lumen. Located in endoplasmic reticulum. Orthologous to human SLC30A5 (solute carrier family 30 member 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See slc-30A5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
9
Sequence:
Chromosome: I; NC_003279.8 (14358562..14367594)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Glutaredoxin domain-containing protein Neighboring gene Endoplasmic reticulum lectin 1 Neighboring gene ncRNA Neighboring gene Enoyl-CoA hydratase, mitochondrial Neighboring gene ncRNA Neighboring gene BBSome complex member BBS1

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables monoatomic cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in intracellular zinc ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular zinc ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in monoatomic cation transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in zinc ion import into Golgi lumen IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in zinc ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in ER to Golgi transport vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Proton-coupled zinc antiporter SLC30A5
NP_740931.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    14358562..14367594
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170935.9NP_740931.2  Proton-coupled zinc antiporter SLC30A5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_740931.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8WQB6
    Conserved Domains (1) summary
    COG1230
    Location:397696
    CzcD; Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]