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rfip-2 FIP-RBD domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173462, updated on 4-Jan-2025

Summary

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Official Symbol
rfip-2
Official Full Name
FIP-RBD domain-containing protein
Primary source
WormBase:WBGene00021456
Locus tag
CELE_Y39F10B.1
See related
AllianceGenome:WB:WBGene00021456
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable small GTPase binding activity. Predicted to be involved in regulated exocytosis. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to several human genes including RAB11FIP1 (RAB11 family interacting protein 1) and RAB11FIP5 (RAB11 family interacting protein 5). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See rfip-2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (723788..732513)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Death domain-containing protein Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene pseudo Neighboring gene F-box C protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing. Ma L, et al. PLoS Genet, 2012. PMID 22829783, Free PMC Article
  2. Loss of heat shock factor initiates intracellular lipid surveillance by actin destabilization. Watterson A, et al. Cell Rep, 2022 Oct 18. PMID 36261024, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulated exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
FIP-RBD domain-containing protein
NP_493798.2
  • Confirmed by transcript evidence
NP_872031.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    723788..732513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061397.5 → NP_493798.2  FIP-RBD domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493798.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B2FD95
    Conserved Domains (1) summary
    cl14603
    Location:62 → 172
    C2; C2 domain

  2. NM_182231.7 → NP_872031.2  FIP-RBD domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_872031.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B2FD96
    Conserved Domains (1) summary
    cl14603
    Location:13 → 123
    C2; C2 domain
Nucleotide Protein
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