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copb-1 Coatomer subunit beta [ Caenorhabditis elegans ]

Gene ID: 173656, updated on 2-Nov-2024

Summary

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Official Symbol
copb-1
Official Full Name
Coatomer subunit beta
Primary source
WormBase:WBGene00021292
Locus tag
CELE_Y25C1A.5
See related
AllianceGenome:WB:WBGene00021292
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable structural molecule activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intra-Golgi vesicle-mediated transport. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Is expressed in several structures, including enteric muscle; excretory cell; intestine; pharynx; and vulval muscle. Orthologous to human COPB1 (COPI coat complex subunit beta 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See copb-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (3078796..3087682)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Protein YIPF;Yip1 domain-containing protein Neighboring gene Zinc finger Ran-binding domain-containing protein 2 Neighboring gene ncRNA Neighboring gene Serpentine receptor class gamma Neighboring gene Serpentine receptor class gamma

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. AP-1 Recruits SMAP-1/SMAPs to the trans-Golgi Network to Promote Sorting in Polarized Epithelia. Wang S, et al. Front Cell Dev Biol, 2021. PMID 34901019, Free PMC Article
  2. The small GTPase Arf1 modulates mitochondrial morphology and function. Ackema KB, et al. EMBO J, 2014 Nov 18. PMID 25190516, Free PMC Article
  3. A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges. Rehain-Bell K, et al. Curr Biol, 2017 Mar 20. PMID 28285996, Free PMC Article
  4. Robust co-immunoprecipitation with mass spectrometry for Caenorhabditis elegans using solid-phase enhanced sample preparation. Baytek G, et al. Biotechniques, 2022 May. PMID 35297663
  5. Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Skop AR, et al. Science, 2004 Jul 2. PMID 15166316, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of COPI vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of COPI vesicle coat IEA
Inferred from Electronic Annotation
more info
  
located_in COPI-coated vesicle membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of membrane coat IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Coatomer subunit beta
NP_494441.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    3078796..3087682
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_062040.9 → NP_494441.1  Coatomer subunit beta [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_494441.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TYL9
    Conserved Domains (4) summary
    COG5096
    Location:31 → 935
    COG5096; Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport]
    pfam07718
    Location:677 → 816
    Coatamer_beta_C; Coatomer beta C-terminal region
    pfam14806
    Location:825 → 953
    Coatomer_b_Cpla; Coatomer beta subunit appendage platform
    sd00044
    Location:138 → 162
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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