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mtch-1 Mitochondrial carrier [ Caenorhabditis elegans ]

Gene ID: 174207, updated on 2-Nov-2024

Summary

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Official Symbol
mtch-1
Official Full Name
Mitochondrial carrier
Primary source
WormBase:WBGene00018395
Locus tag
CELE_F43E2.7
See related
AllianceGenome:WB:WBGene00018395
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane and mitochondrion. Is expressed in several structures, including enteric muscle; intestine; nervous system; pharynx; and rectal epithelium. Orthologous to human MTCH1 (mitochondrial carrier 1) and MTCH2 (mitochondrial carrier 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mtch-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (7372615..7374166, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Peptidylprolyl isomerase Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene RNA polymerase Rpb4/RPC9 core domain-containing protein Neighboring gene PAP-associated domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Loss of MTCH-1 suppresses age-related proteostasis collapse through the inhibition of programmed cell death factors. Aman Y, et al. Cell Rep, 2022 Nov 22. PMID 36417880
  2. Lifespan regulation by evolutionarily conserved genes essential for viability. Curran SP, et al. PLoS Genet, 2007 Apr 6. PMID 17411345, Free PMC Article
  3. SAFER, an Analysis Method of Quantitative Proteomic Data, Reveals New Interactors of the C. elegans Autophagic Protein LGG-1. Yi Z, et al. J Proteome Res, 2016 May 6. PMID 26999449
  4. The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo. Du Z, et al. Dev Cell, 2015 Sep 14. PMID 26321128, Free PMC Article
  5. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mitochondrial carrier
NP_001364693.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    7372615..7374166 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001377817.2 → NP_001364693.1  Mitochondrial carrier [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2KYJ5
Nucleotide Protein
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